2026-04-18T03:48:25Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/106252025-10-24T08:28:17Zcom_2072_451660com_2072_378040col_2072_451662

Eye movements in patients with post-COVID condition Vinuela-Navarro, Valldeflors Goset, Joan Aldaba, Mikel Mestre, Clara Rovira-Gay, Cristina Vilaseca, Meritxell Cano Marco, Neus Ariza, Mar Delas, Barbara Garolera, Maite [Vinuela-Navarro V, Goset J, Aldaba M, Mestre C, Rovira-Gay C, Vilaseca M] Center for Sensors, Instruments and Systems Development, Universitat Politècnica de Catalunya, Terrassa, Spain. [Cano N] Grup d'Investigació Clínica per a Cervell, Cognició i Comportament, Hospital de Terrassa, Consorci Sanitari de Terrassa, Terrassa, Spain. Departament de Ciències Bàsiques, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain. [Ariza M] Grup d'Investigació Clínica per a Cervell, Cognició i Comportament, Hospital de Terrassa, Consorci Sanitari de Terrassa, Terrassa, Spain. [Delàs B] Servei d'Oftalmologia, Hospital de Terrassa, Consorci Sanitari de Terrassa, Terrassa, Spain. [Garolera M] Grup d'Investigació Clínica per a Cervell, Cognició i Comportament, Hospital de Terrassa, Consorci Sanitari de Terrassa, Terrassa, Spain. Unitat de Neuropsicologia, Hospital de Terrassa, Consorci Sanitari de Terrassa, Terrassa, Spain Consorci Sanitari de Terrassa Tests neuropsicològics COVID-19 (Malaltia) Ulls - Moviments DISEASES::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections PHENOMENA AND PROCESSES::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Movement::Eye Movements PSYCHIATRY AND PSYCHOLOGY::Behavioral Disciplines and Activities::Psychological Tests::Neuropsychological Tests ENFERMEDADES::virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus FENÓMENOS Y PROCESOS::fenómenos fisiológicos nerviosos y musculoesqueléticos::fenómenos fisiológicos musculoesqueléticos::movimiento::movimientos oculares PSIQUIATRÍA Y PSICOLOGÍA::disciplinas y actividades conductuales::pruebas psicológicas::pruebas neuropsicológicas COVID-19; Eye movements; Pupil response COVID-19; Movimientos oculares; Respuesta pupilar COVID-19; Moviments oculars; Resposta pupil·lar Eye movement control is impaired in some neurological conditions, but the impact of COVID-19 on eye movements remains unknown. This study aims to investigate differences in oculomotor function and pupil response in individuals who suffer post-COVID-19 condition (PCC) with cognitive deficits. Saccades, smooth pursuit, fixation, vergence and pupillary response were recorded using an eye tracker. Eye movements and pupil response parameters were computed. Data from 16 controls, 38 COVID mild (home recovery) and 19 COVID severe (hospital admission) participants were analyzed. Saccadic latencies were shorter in controls (183 ± 54 ms) than in COVID mild (236 ± 83 ms) and COVID severe (227 ± 42 ms) participants (p = 0.017). Fixation stability was poorer in COVID mild participants (Bivariate Contour Ellipse Area of 0.80 ± 1.61°2 vs 0.36 ± 0.65 °2 for controls, p = 0.019), while percentage of pupil area reduction/enlargement was reduced in COVID severe participants (39.7 ± 12.7%/31.6 ± 12.7% compared to 51.7 ± 22.0%/49.1 ± 20.7% in controls, p < 0.015). The characteristics of oculomotor alterations found in PCC may be useful to understand different pathophysiologic mechanisms. Project PID2020-112527RB-I00 funded by MCIN/AEI/10.13039/501100011033; La Marató de TV3 Foundation (202111-30-31-32). 2023-11-20T10:47:20Z 2023-11-20T10:47:20Z 2023-07-07 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Vinuela-Navarro V, Goset J, Aldaba M, Mestre C, Rovira-Gay C, Cano N, et al. Eye movements in patients with post-COVID condition. Biomed Opt Express. 2023 Jul 7;14(8):3936-49. https://hdl.handle.net/11351/10625 10.1364/BOE.489037 37799689 http://hdl.handle.net/11351/10625 eng Biomedical Optics Express;14(8) https://doi.org/10.1364/boe.489037 Attribution-NonCommercial 4.0 International http://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess application/pdf Optica Publishing Group Scientia