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oai:recercat.cat:11351/106012025-10-24T10:16:14Zcom_2072_378070com_2072_378040col_2072_378092

2025-10-24T10:16:14Z urn:hdl:11351/10601 Tractional Retinal Detachment Related to Hemoglobin C Trait Retinopathy: A Case Report Garrell Salat, Xavier Garcia-Arumi, Claudia Bertolani, Yann Banderas García, Sandra Buck Sainz-Rozas, Pablo Garcia-Arumi, Jose Despreniment de retina Hemoglobina Anèmia hemolítica Angiografia DISEASES::Eye Diseases::Retinal Diseases::Retinal Detachment DISEASES::Hemic and Lymphatic Diseases::Hematologic Diseases::Anemia::Anemia, Hemolytic::Anemia, Hemolytic, Congenital::Hemoglobin C Disease ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Radiography::Angiography ENFERMEDADES::oftalmopatías::enfermedades de la retina::desprendimiento de retina ENFERMEDADES::enfermedades hematológicas y linfáticas::enfermedades hematológicas::anemia::anemia hemolítica::anemia hemolítica congénita::enfermedad de la hemooglobina C TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::técnicas y procedimientos diagnósticos::diagnóstico por imagen::radiografía::angiografía Hemoglobin C trait; Retinal detachment; Sickle cell retinopathy Rasgo de hemoglobina C; Desprendimiento de retina; Retinopatía de células falciformes Tret de l'hemoglobina C; Despreniment de retina; Retinopatia de cèl·lules falciformes Hemoglobin C (HbC) disease is an uncommon disease that is generally considered benign, causing only occasionally painless hematuria, osteomyelitis, and dental abnormalities. Ocular manifestations have rarely been described in these patients. Here we report a novel ophthalmological manifestation of the disease. A 20-year-old woman presented with progressive visual loss in her right eye due to tractional retinal detachment. The left eye was apparently normal, but wide-field fluorescence angiography showed mild peripheral ischemia with multiple vascular abnormalities. Vitrectomy was performed and the systemic workup revealed the presence of hemoglobinopathy C in heterozygous form. HbC disease can be sight-threating due to retinal proliferation, similar to sickle cell retinopathy. Patients affected with this disease should undergo regular surveillance. Ultra-wide angiography is a helpful examination to detect peripheral ischemia in the earlier stages. 2025-10-24T10:16:14Z 2025-10-24T10:16:14Z 2023-11-14T08:31:54Z 2023-11-14T08:31:54Z 2023-10-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/11351/10601 Turkish Journal of Ophthalmology;53(5) https://doi.org/10.4274/tjo.galenos.2023.48672 Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Galenos Publishing House Scientia