2026-04-14T03:06:26Zhttps://recercat.cat/oai/requestoai:recercat.cat:11351/103902025-10-24T10:20:54Zcom_2072_378070com_2072_378040col_2072_378092
RECERCAT
author
CALVO ORTEGA, JUAN FRANCISCO
author
Hermida López, Marcelino
2025-10-24T10:20:54Z
2025-10-24T10:20:54Z
2023-10-02T10:33:29Z2023-10-02T10:33:29Z2023-07-24
http://hdl.handle.net/11351/10390
Monte Carlo; CommissioningMonte Carlo; Puesta en marchaMonte Carlo; Posada en marxaBackground:
The purpose was to validate the PRIMO Monte Carlo software to be used during the commissioning of a TPS.
Materials and methods:
The Acuros XB v. 16.1 algorithm of the Eclipse was configured for 6 MV and 6 MV flattening-filter-free (FFF) photon beams, from a TrueBeam linac equipped with a high-definition 120-leaf multileaf collimator (MLC). PRIMO v. 0.3.64.1814 software was used with the phase space files provided by Varian and benchmarked against the reference dosimetry dataset published by the Imaging and Radiation Oncology Core–Houston (IROC-H).
Thirty Eclipse clinical intensity-modulated radiation therapy (IMRT)/volumetric modulated arc therapy (VMAT) plans were verified in three ways: 1) using the PTW Octavius 4D (O4D) system; 2) the Varian Portal Dosimetry system and 3) the PRIMO software. Clinical validation of PRIMO was completed by comparing the simulated dose distributions on the O4D phantom against dose measurements for these 30 clinical plans. Agreement evaluations were performed using a 3% global/2 mm gamma index analysis.
Results:
PRIMO simulations agreed with the benchmark IROC-H data within 2.0% for both energies.
Gamma passing rates (GPRs) from the 30 clinical plan verifications were (6 MV/6MV FFF): 99.4% ± 0.5%/99.9% ± 0.1%, 99.8% ± 0.4% /98.9% ± 1.4%, 99.7% ± 0.4%/99.7% ± 0.4%, for the 1), 2) and 3) verification methods, respectively. Agreement between PRIMO simulations on the O4D phantom and 3D dose measurements resulted in GPRs of 97.9% ± 2.4%/ 99.7% ± 0.4%.
Conclusion:
The PRIMO software is a valuable tool for dosimetric verification of clinical plans during the commissioning of the primary TPS.
Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess
Radioteràpia
Programari
Radiació - Dosimetria
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Therapy, Computer-Assisted::Radiotherapy Planning, Computer-Assisted
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::tratamiento asistido por ordenador::planificación radioterápica asistida por ordenador
PRIMO Monte Carlo software as a tool for commissioning of an external beam radiotherapy treatment planning system
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion