2026-04-17T05:45:41Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/102332024-06-06T08:39:28Zcom_2072_378070com_2072_378040col_2072_378092

00925njm 22002777a 4500 dc Carrasco, Juan Antonio author Marquina, Gloria author Martinez-Garcia, Jeronimo author MARTÍNEZ MARÍN, VIRGINIA author ALVAREZ, ROSA author Serrano, Cesar author 2023-09-05T12:07:25Z 2023-09-05T12:07:25Z 2023-09 Avapritinib; Imatinib; Ripretinib Avapritinib; Imatinib; Ripretinib Avapritinib; Imatinib; Ripretinib Gastrointestinal stromal tumor (GIST) is the most common malignant neoplasm of mesenchymal origin, and a paradigmatic model for a successful rational development of targeted therapies in cancer. The introduction of tyrosine kinase inhibitors with activity against KIT/PDGFRA in both localized and advanced stages has remarkably improved the survival in a disease formerly deemed resistant to all systemic therapies. These guidelines are elaborated by the conjoint effort of the Spanish Society of Medical Oncology (SEOM) and the Spanish Sarcoma Research Group (GEIS) and provide a multidisciplinary and updated consensus for the diagnosis and treatment of GIST patients. We strongly encourage that the managing of these patients should be performed within multidisciplinary teams in reference centers. Decisió de grup Tracte gastrointestinal - Càncer - Tractament Tracte gastrointestinal - Càncer - Diagnòstic DISEASES::Digestive System Diseases::Digestive System Neoplasms::Gastrointestinal Neoplasms::Digestive System Diseases::Gastrointestinal Stromal Tumors PUBLIC HEALTH::Health Care (Public Health)::Delivery of Health Care::Disease Management PSYCHIATRY AND PSYCHOLOGY::Behavior and Behavior Mechanisms::Psychology, Social::Group Processes::Consensus ENFERMEDADES::enfermedades del sistema digestivo::neoplasias del sistema digestivo::neoplasias gastrointestinales::enfermedades del sistema digestivo::tumores del estroma gastrointestinal SALUD PÚBLICA::atención a la salud (salud pública)::prestación sanitaria::tratamiento de las enfermedades PSIQUIATRÍA Y PSICOLOGÍA::conducta y mecanismos de la conducta::psicología social::procesos de grupo::consenso SEOM-GEIS clinical guideline for gastrointestinal stromal tumors (2022)