2026-04-13T00:07:41Zhttps://recercat.cat/oai/requestoai:recercat.cat:11351/102222024-12-13T10:29:25Zcom_2072_378070com_2072_378040col_2072_378092
RECERCAT
author
Mizab Mellah, Chadia
author
Sánchez, Enric
author
Gutiérrez Carrasquilla, Liliana
author
Balsells, Núria
author
Arqué, Anaïs
author
Ruano Esteban, Raquel
author
Hernández Pascual, Cristina
author
Simó Canonge, Rafael
2023-11-06T10:28:43Z
2023-11-06T10:28:43Z
2023-09-04T12:26:34Z2023-09-04T12:26:34Z2023-08-10
http://hdl.handle.net/11351/10222
Diabetes complications; Questionnaires; Respiratory symptomsComplicaciones de la diabetes; Questionarios; Síntomas respiratoriosComplicacions de la diabetis; Qüestionaris; Símptomes respiratorisIntroduction: Individuals with type 2 diabetes (T2D) should be considered a susceptible group for pulmonary dysfunction. So, we aimed to evaluate the sensation of breathlessness in this population by administering two well-validated questionnaires.
Methods: This is a crosssectional study with 592 people without known respiratory disease (353 with T2D) who answered the modified Medical Research Council (mMRC) questionnaire. In addition, 47% also responded to the St George Respiratory Questionnaire, a specific instrument designed to be applied to patients with obstructive airway disease.
Results: Patients with T2D showed a higher mMRC score in comparison to the control group [1.0 (0.0 – 4.0) vs. 0.0 (0.0 – 4.0), p<0.001]. A higher prevalence of subjects with mMRC ≥2 was observed in T2D that in the control group (20.2% vs. 11.6%, p=0.004). Participants with T2D and mMRC ≥2 showed a higher HbA1c (8.2 ± 1.6% vs. 7.8 ± 1.6%, p=0.048), longer T2D evolution and higher prevalence of nephropathy. In the multivariate analysis, the presence of T2D [OR=1.95 (1.19 to 3.22), p=0.008] in all the population, and HbA1c [OR=1.19 (1.01 to 1.41), p=0.034] and the presence of diabetic nephropathy [OR=2.00 (1.14 to 3.52), p=0.015] in patients with T2D, predicted a mMRC ≥2. Finally, no differences were observed regarding the SGRQ score among groups.
Conclusions: Patients with T2D showed a greater sensation of dyspnea than subjects with normal carbohydrate metabolism. Risk factors included poor metabolic control and the presence of renal disease.This research was supported by grants from Instituto de Salud Carlos III (PI15/00260), Fondos FEDER “Una manera de hacer Europa”), and Sociedad Española de Endocrinología y Nutrición. CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM) is an initiative of the Instituto Carlos III.
Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess
Diabetis no-insulinodependent - Complicacions
Dispnea
DISEASES::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus, Type 2
Other subheadings::Other subheadings::Other subheadings::/complications
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors
DISEASES::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Signs and Symptoms, Respiratory::Dyspnea
ENFERMEDADES::enfermedades del sistema endocrino::diabetes mellitus::diabetes mellitus tipo II
Otros calificadores::Otros calificadores::Otros calificadores::/complicaciones
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::estadística como asunto::probabilidad::riesgo::factores de riesgo
ENFERMEDADES::afecciones patológicas, signos y síntomas::signos y síntomas::signos y síntomas respiratorios::disnea
Assessment of dyspneic sensation in patients with type 2 diabetes
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion