2026-04-14T03:25:18Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/101252025-10-24T10:41:30Zcom_2072_378070com_2072_378040col_2072_378092

Multisocietal European consensus on the terminology, diagnosis, and management of patients with synchronous colorectal cancer and liver metastases: an E-AHPBA consensus in partnership with ESSO, ESCP, ESGAR, and CIRSE Siriwardena, Ajith Serrablo, Alejandro Fretland, Åsmund Avdem Wigmore, Stephen Ramia, Jose Malik, Hassan Pellino, Gianluca Institut Català de la Salut [Siriwardena AK] Hepato-Pancreato-Biliary Unit, Manchester Royal Infirmary, Manchester, UK. [Serrablo A] Department of Surgery, Miguel Servet University Hospital, Zaragoza, Spain. [Fretland ÅA] Department of Surgery, Oslo University Hospital, Oslo, Norway. [Wigmore SJ] Hepatobiliary and Liver Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, UK. [Ramia-Angel JM] Department of Surgery, University Hospital of Guadalajara, Guadalajara, Spain. [Malik HZ] Liver Surgery Unit, Royal Liverpool University Hospital, Liverpool, UK. [Pellino G] Unitat de Cirurgia de Còlon i Recte, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Department of Advanced Medical and Surgical Sciences, Università degli Studi della Campania ‘Luigi Vanvitelli’, Naples, Italy Vall d'Hebron Barcelona Hospital Campus Decisió de grup Còlon - Càncer - Diagnòstic Recte - Càncer - Diagnòstic DISEASES::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms Other subheadings::Other subheadings::/diagnosis DISEASES::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Liver Neoplasms PSYCHIATRY AND PSYCHOLOGY::Behavior and Behavior Mechanisms::Psychology, Social::Group Processes::Consensus ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias del sistema digestivo::neoplasias gastrointestinales::neoplasias intestinales::neoplasias colorrectales Otros calificadores::Otros calificadores::/diagnóstico ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias del sistema digestivo::neoplasias hepáticas PSIQUIATRÍA Y PSICOLOGÍA::conducta y mecanismos de la conducta::psicología social::procesos de grupo::consenso Consensus; Colorectal cancer; Liver metastases Consens; Càncer colorectal; Metàstasis hepàtiques Consenso; Cáncer colorrectal; Metástasis hepáticas Background Contemporary management of patients with synchronous colorectal cancer and liver metastases is complex. The aim of this project was to provide a practical framework for care of patients with synchronous colorectal cancer and liver metastases, with a focus on terminology, diagnosis, and management. Methods This project was a multiorganizational, multidisciplinary consensus. The consensus group produced statements which focused on terminology, diagnosis, and management. Statements were refined during an online Delphi process, and those with 70 per cent agreement or above were reviewed at a final meeting. Iterations of the report were shared by electronic mail to arrive at a final agreed document comprising 12 key statements. Results Synchronous liver metastases are those detected at the time of presentation of the primary tumour. The term ‘early metachronous metastases' applies to those absent at presentation but detected within 12 months of diagnosis of the primary tumour, the term ‘late metachronous metastases’ applies to those detected after 12 months. ‘Disappearing metastases’ applies to lesions that are no longer detectable on MRI after systemic chemotherapy. Guidance was provided on the recommended composition of tumour boards, and clinical assessment in emergency and elective settings. The consensus focused on treatment pathways, including systemic chemotherapy, synchronous surgery, and the staged approach with either colorectal or liver-directed surgery as first step. Management of pulmonary metastases and the role of minimally invasive surgery was discussed. Conclusion The recommendations of this contemporary consensus provide information of practical value to clinicians managing patients with synchronous colorectal cancer and liver metastases. 2023-08-23T07:00:27Z 2023-08-23T07:00:27Z 2023-08-11 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Siriwardena AK, Serrablo A, Fretland ÅA, Wigmore SJ, Ramia-Angel JM, Malik HZ, et al. Multisocietal European consensus on the terminology, diagnosis, and management of patients with synchronous colorectal cancer and liver metastases: an E-AHPBA consensus in partnership with ESSO, ESCP, ESGAR, and CIRSE. Br J Surg. 2023 Sep;110(9):1161–70. 1365-2168 https://hdl.handle.net/11351/10125 10.1093/bjs/znad124 37442562 http://hdl.handle.net/11351/10125 eng British Journal of Surgery;110(9) https://doi.org/10.1093/bjs/znad124 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess application/pdf application/pdf Oxford University Press Scientia