2026-04-17T00:52:53Zhttps://recercat.cat/oai/requestoai:recercat.cat:10459.1/840212024-12-05T22:04:48Zcom_2072_3622col_2072_479130
RECERCAT
author
Pelegrin-Valls, Jonathan
author
Álvarez Rodríguez, Javier
author
Martín-Alonso, María José
author
Ramírez, Gustavo A.
author
Baila, Claudia
author
Lobón, Sandra
author
Joy, Margalida
author
Serrano, Beatriz
2024-12-05T22:04:48Z
2024-12-05T22:04:48Z
2022-10-27T11:48:01Z2022-10-27T11:48:01Z2022-10-142022-10-27T11:48:01Z
http://hdl.handle.net/10459.1/84021
Ewes fed sainfoin (a source of condensed tannins "CT") may influence the homeostasis of the gastrointestinal tract of suckling lambs. This study investigated the effects of CT from sainfoin in the maternal diet on plasma fructosamine, faecal coccidian excretion, and gene expression of immune and antioxidant markers in jejunum and ileum of suckling lambs. Twelve Rasa Aragonesa lambs with their dams were selected. The maternal diet was based on fresh sainfoin (SAINFOIN, n = 6) and sainfoin + polyethylene-glycol (SAINFOIN + PEG, as a CT-binder, n = 6) plus a daily supplement of 200 g barley in both groups. A lower percentage of lambs that shed more than 10 oocysts/g faeces was observed in SAINFOIN compared to the SAINFOIN + PEG group (p = 0.07). Jejunal gene expression of transforming growth factor-β1, tumour necrosis factor-α, and glutathione peroxidase (GPX) 1 and 4 were lower in the SAINFOIN group (p < 0.05). In contrast, ileal catalase and GPX2 expression were increased in the SAINFOIN group (p < 0.05). Overall, the results suggest that the presence of CT in the dams' diets has a positive effect on reducing excreted coccidian oocysts and favours antioxidant-immune crosstalk at gut level in suckling lambs.This research was funded by the Ministry of Science, Innovation and Universities of Spain and the European Regional Development Funds, grant number INIA RTA2017-00008-C02-01 and 02.
cc-by (c) Pelegrin-Valls et al., 2022 info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/4.0/
Suckling lambs
Sainfoin
Condensed tannins;
Immune response
Oxidative stress
Coccidiosis
Effect of Maternal Dietary Condensed Tannins from Sainfoin (Onobrychis viciifolia) on Gut Health and Antioxidant-Immune Crosstalk in Suckling Lambs
info:eu-repo/semantics/article publishedVersion