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oai:recercat.cat:10459.1/730582024-12-05T21:45:13Zcom_2072_3622col_2072_479130

2024-12-05T21:45:13Z urn:hdl:10459.1/73058 Amyloid fibrils from organic solutions of an amphiphilic dipeptide Casanovas Salas, Jordi Mayans Tayadella, Enric Díaz Andrade, Angélica María Martínez Gil, Ana Jimenez Sanz, Ana Isabel Cativiela, Carlos Puiggalí Bellalta, Jordi Alemán Llansó, Carlos Solució (Química) Non-hydrated organic solutions of a diphenylalanine amphiphile blocked at the C-terminus with a fluorenylmethyl ester and stabilized at the N-terminus with a trifluoroacetate have been used to prepare amyloid fibrils. The solvent used to prepare the stock solution together with the co-solvent added enables regulation of the characteristics of the fibrils, which is important for their use in technological applications. This work was supported by MINECO (RTI2018-098951-B- I00, RTI2018-101827-B-I00, and CTQ2013-40855-R), the Agència de Gestió d’Ajuts Universitaris i de Recerca (2017SGR359 and 2017SGR373) and Gobierno de Aragon-FEDER (research group Aminoacidos y Peptidos E19_17R). Support for the research of C. A. was received through the prize ‘‘ICREA Academia’’ for excellence in research funded by the Generalitat de Catalunya. 2024-12-05T21:45:13Z 2024-12-05T21:45:13Z 2022-02-22T12:19:02Z 2022-02-22T12:19:02Z 2019 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion http://hdl.handle.net/10459.1/73058 MINECO/PN2017-2020/RTI2018-098951-B-I00 MINECO/PN2017-2020/RTI2018-101827-B-I00 MINECO/PN2013-2016/CTQ2013-40855-R Versió postprint del document publicat a https://doi.org/10.1039/c9cc04139g Chemical communications, 2019, vol. 55, p. 8556-8559 (c) Royal Society of Chemistry, 2019 info:eu-repo/semantics/openAccess Royal Society of Chemistry