2026-04-14T06:12:18Zhttps://recercat.cat/oai/request

oai:recercat.cat:10459.1/726212024-12-05T21:42:22Zcom_2072_3622col_2072_479130

00925njm 22002777a 4500 dc Servià Goixart, Lluís author Llompart-Pou, Juan Antonio author Chico-Fernández, Mario author Montserrat, Neus author Badia Castello, Mariona author Barea-Mendoza, Jesús Abelardo author Ballesteros Sanz, María Ángeles author Trujillano Cabello, Javier author 2021-12-22T09:43:56Z 2021-12-22T09:43:56Z 2021 Background : Severity scores are commonly used for outcome adjustment and benchmarking of trauma care provided. No specific models performed only with critically ill patients are available. Our objective was to develop a new score for early mortality prediction in trauma ICU patients. Methods: This is a retrospective study using the Spanish Trauma ICU registry (RETRAUCI) 2015–2019. Patients were divided and analysed into the derivation (2015–2017) and validation sets (2018–2019). We used as candidate variables to be associated with mortality those available in RETRAUCI that could be collected in the first 24 h after ICU admission. Using logistic regression methodology, a simple score (RETRASCORE) was created with points assigned to each selected variable. The performance of the model was carried out according to global measures, discrimination and calibration. Results: The analysis included 9465 patients: derivation set 5976 and validation set 3489. Thirty-day mortality was 12.2%. The predicted probability of 30-day mortality was determined by the following equation: 1/(1 + exp (− y)), where y = 0.598 (Age 50–65) + 1.239 (Age 66–75) + 2.198 (Age > 75) + 0.349 (PRECOAG) + 0.336 (Pre-hospital intubation) + 0.662 (High-risk mechanism) + 0.950 (unilateral mydriasis) + 3.217 (bilateral mydriasis) + 0.841 (Glasgow ≤ 8) + 0.495 (MAIS-Head) − 0.271 (MAIS-Thorax) + 1.148 (Haemodynamic failure) + 0.708 (Respiratory failure) + 0.567 (Coagulopathy) + 0.580 (Mechanical ventilation) + 0.452 (Massive haemorrhage) − 5.432. The AUROC was 0.913 (0.903–0.923) in the derivation set and 0.929 (0.918–0.940) in the validation set. Conclusions: The newly developed RETRASCORE is an early, easy-to-calculate and specific score to predict in-hospital mortality in trauma ICU patients. Although it has achieved adequate internal validation, it must be externally validated. RETRAUCI was supported by a grant for the development of an electronic web-based system awarded to Dr. Chico-Fernández (Fundación Mutua Madrileña, reference number AP117892013). http://hdl.handle.net/10459.1/72621 Trauma and injury severity score Intensive care unit Mortality Prognostic scoring systems Development of a new score for early mortality prediction in trauma ICU patients: RETRASCORE