2026-04-13T07:24:40Zhttps://recercat.cat/oai/request

oai:recercat.cat:10459.1/704472024-12-05T21:30:25Zcom_2072_3622col_2072_479130

00925njm 22002777a 4500 dc Tor i Naudí, Marc author Vilaró, Francisca author Ros Freixedes, Roger author Álvarez Rodríguez, Javier author Bosch Puig, Lluís author Gol, Sofia author Pena i Subirà, Ramona Natacha author Reixach, Josep author Estany Illa, Joan author 2021-02-05T07:56:46Z 2021-02-05T07:56:46Z 2021-02-03 2021-02-05T07:56:46Z Circulating non-esterified fatty acids (NEFA) can reflect the composition of dietary fat or adipose tissues depending on the fasting conditions. Therefore, circulating NEFA may be valuable as biomarkers for meat quality traits, such as intramuscular fat content and fatty acid composition in finishing pigs. Genetic variants that regulate lipid metabolism can also modulate the circulating NEFA. We conducted an experiment with 150 heavy Duroc pigs to evaluate fluctuations in the circulating NEFA composition due to age, fasting duration and two genetic polymorphisms, one in the leptin receptor (LEPR; rs709596309) and one in the stearoyl-CoA desaturase (SCD; rs80912566) gene. Circulating NEFA were more saturated and less monounsaturated than the subcutaneous and intramuscular adipose tissues. Absolute circulating NEFA content was more influenced by fasting duration than age. The SCD polymorphism did not impact NEFA content or composition. The LEPR polymorphism affected the content but not the fatty acid composition. Circulating oleic acid NEFA content after a short fasting was positively correlated with intramuscular fat content and, after a long fasting, with intramuscular oleic acid content. We conclude that circulating NEFA reflect environmental and genetic metabolic changes but are of limited value as biomarkers for intramuscular fat content and fatty acid composition. This Research was founded by the Spanish Ministry of Economy and Competitiveness and the European Union Regional Development Funds (grants AGL2012-33529, AGL2015-65846-R, and RTI2018-101346-B-I00). http://hdl.handle.net/10459.1/70447 Non-esterified fatty acids Intramuscular fat Oleic acid Fatty acid composition Stearoyl-CoA desaturase Leptin receptor Meat quality Circulating non-esterified fatty acids as biomarkers for fat content and composition in pigs