2026-04-14T07:24:43Zhttps://recercat.cat/oai/requestoai:recercat.cat:10459.1/695952024-12-05T22:48:45Zcom_2072_3622col_2072_479130
New Metrics to Assess Type 2 Diabetes after Bariatric Surgery: The “Time-Within-Remission Range”
de Hollanda, Ana
Lecube Torelló, Albert
Rubio, Miguel Ángel
Sánchez Peña, Enric
Vilarrasa, Núria
Gregorio Oliva, José
Fernández-Soto, María Luisa
Salas-Salvadó, Jordi
Ballesteros-Pomar, María D.
Ciudin, Andreea
Torres, Ferran
Vidal, Concepción
Morales, María José
Valdés, Sergio
Pellitero, Silvia
Miñambres, Inka
Masmiquel, Lluís
Goday, Albert
Suarez, Lorena
Flores, Lilliam
Bueno Díez, Marta
Caixàs, Assumpta
Bretón, Irene
Cámara, Rosa
Olbeyra, Romina
Penso, Rona
de la Cruz, María José
Simó-Servat, Andreu
Pereyra-García, Francisca María
López-Mezquita, Elena Teresa
Gils, Anna
Fidilio, Enzamaria
Bandrés, Orosia
Martínez, Ángel
Abuín, Jose
Marques-Pamies, Montserrat
Tuneu, Laura
Arteaga, Magdalena
Castañer, Olga
Goñi, Fernando
Arrizabalaga, Cristina
Botana, Manuel Antonio
Calañas, Alfonso
Bariatric surgery
Time-within-remission range
Type 2 diabetes
Metabolic control
Almost one third of patients do not achieve type 2 diabetes remission after bariatric surgery
or are unable to sustain this effect long term. Our objective was to delve further into the dynamic
responses of diabetes after bariatric surgery and to evaluate the “time-within-remission range” as a
variable of metabolic control. A descriptive cohort study was done using a computerised multicentre
and multidisciplinary registry. All data were adjusted by propensity score. A total of 1186 subjects
with a follow-up of 4.5 ± 2.5 years were included. Type of surgery, diabetes remission, recurrence
of diabetes, “time-within-remission range” and key predictors of diabetes outcomes were assessed.
All patients (70% women, 51.4 ± 9.2 years old, body mass index (BMI) 46.3 ± 6.9 kg/m2
) underwent
primary bariatric procedures. “Time-within-remission range” were 83.3% (33.3–91.6) after gastric
bypass, 68.7% (7.1–87.5) after sleeve gastrectomy and 90% (83.3–92.8) after malabsorptive techniques
(p < 0.001 for all). Duration of diabetes, baseline HbA1c and insulin treatment were significantly
negatively correlated with the “time-within-remission range”. The association of bariatric techniques
with “time-within-remission range”, using gastric bypass as a reference, were: odds ratio (OR) 3.70
(2.34–5.84), p < 0.001 for malabsorptive techniques and OR 0.55 (0.40–0.75), p < 0.001 for sleeve
gastrectomy. Characteristics of type 2 diabetes powerfully influence the outcomes of bariatric
surgery. The “time-within-remission range” unveils a superiority of gastric bypass compared to
sleeve gastrectomy
This study was supported by the Spanish Society of Endocrinology and Nutrition (SEEN). The RICIBA and RICIBA-DM are property of the Spanish Society of Endocrinology and Nutrition (SEEN). J.S.S. gratefully acknowledges the financial support by ICREA under the ICREA Academia programme.
2020-10-02T08:28:57Z
2020-10-02T08:28:57Z
2020
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
https://doi.org/10.3390/jcm9041070
2077-0383
http://hdl.handle.net/10459.1/69595
http://hdl.handle.net/10459.1/69595
eng
https://doi.org/10.3390/jcm9041070
Journal of Clinical Medicine, 2020, vol. 9, núm. 4, p. 1070
cc-by (c) de Hollanda, Ana et al., 2020
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
MDPI