2026-04-14T02:07:11Zhttps://recercat.cat/oai/request

oai:recercat.cat:10459.1/4689032025-10-27T19:49:10Zcom_2072_3622col_2072_479130

00925njm 22002777a 4500 dc Godoy i García, Pere author Pardos Plaza, Jéssica author García Cenoz, Manuel author Parrón, Ignacio author Martínez-Baz, Iván author Ferras, Joaquin author Rius, Cristina author Godoy, Sofía author Toledo, Diana author Sanz, Inma author Follia, Núria author Miret, Carme author Alsedà Graells, Miquel author Plans-Rubio, Pedro author Carol, Monica author Bes, Núria author Sala i Farré, M Rosa author Caylà, Joan A. author Muñoz-Almagro, Carmen author Castilla, Jesús author Domínguez García, Àngela author 2025-10-06 The objective of this study was to evaluate the impact on SARS-CoV-2 transmission prevention of mask wearing by index cases and their household contacts. A prospective study of SARS-CoV-2 transmission to household contacts aged ≥18 years was conducted between May 2022 and February 2024 in Spain. Contacts underwent a rapid antigen test on day zero and a real-time polymerase chain reaction test 7 days later if results were negative. The dependent variable was SARS-CoV-2 infection in contacts. Index case and contact mask use effects were estimated using the adjusted odds ratio (aOR) and its 95% confidence interval (CI). Studied were 230 household contacts, mean (standard deviation) age 53.3 (16.6) years, and 47.8% (110/230) women. Following index case diagnosis, 36.1% of contacts (83/230) used a mask, and 54.3% (125/230) were exposed to a mask-wearing index case. Infection incidence in contacts was 45.2% (104/230) and was lower in contacts exposed to mask-wearing index cases (36.0% vs. 56.2%; p < 0.002). The logistic regression model indicated a protective effect for contacts of both index case mask use (aOR = 0.31; 95% CI: 0.15–0.65) and vaccination (aOR = 0.24; 95% CI: 0.08–0.77). Index case mask use reduced SARS-CoV-2 transmission to contacts, while mask effectiveness was not observed for contacts. This study was funded by the Instituto de Salud Carlos III (ISCIII) via project PI21/01883 (co-funded by the European Union) and the Centre for Networked Biomedical Research – Epidemiology and Public Health (CIBERESP) via project ESP22PI01. http://hdl.handle.net/10459.1/468903 COVID-19 Facemask Household contact SARS-CoV2 Mask wearing by COVID-19 index cases reduces SARS-CoV-2 transmission to household contacts