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00925njm 22002777a 4500 dc Llovera i Tomàs, Marta author Gouveia, Leonor author Zorzano, Antonio author Sanchis, Daniel author 2024 Ministerio de Ciencia e Innovación (MICINN), Gobierno de España, grant numbers PID2019-104509RB-I00 and PID2022-139965OB-100, and AGAUR, Generalitat de Catalunya, Catalunya, grant number 2021_SGR_00758 support the research in ML and DS laboratory. MICINN grant number PID2022-137576OB-I00 to A.Z. PERMISSIONS: Oxford University Press permits reproduction of Figure 4 panels c and e from Pardo et al.9 in Fig. 2, with License number 5676540546080. Lipid Metabolism Mitochondria Protein Transport The effects of ENDOG on lipid metabolism may be tissue-dependent and may not require its translocation from mitochondria