2026-04-17T14:45:57Zhttps://recercat.cat/oai/request

oai:recercat.cat:10459.1/4632562025-09-15T18:43:38Zcom_2072_3622col_2072_479130

00925njm 22002777a 4500 dc Castillo García, María author Solano Pérez, Esther author Romero Peralta, Sofía author Viejo Ayuso, María Esther author Silgado Martínez, Laura author Álvarez Balado, Leticia author Mediano San Andrés, Rosa author Resano, Pilar author Cano-Pumarega, Irene author Sánchez de la Torre, Manuel author Ortigado, Alfonso author López Dueñas, Ana author Fidalgo, Laura author Rodríguez, Ángel author Mediano, Olga author 2022 Current data support an increase in the prevalence of high blood pressure (HBP) in pediatric patients with sleep-disordered breathing (SDB). Adeno-tonsillectomy has been shown to be an effective treatment for most patients. Our objective was to determine the prevalence of HBP in pediatric patients with SDB and the impact of adeno-tonsillectomy with a multicenter, longitudinal, and prospective study that included 286 children referred for suspected SDB. The diagnosis of SDB was established by polysomnography (PSG) and the diagnosis of HBP by 24-h ambulatory blood pressure monitoring (ABPM). In patients without SDB and SDB without treatment indication, these tests were repeated six months after the baseline visit. For patients with medical treatment for SDB, the tests were repeated six months after the treatment initiation. Finally, in patients with surgery indication, ABPM was performed just before surgical treatment and ABPM and PSG six months after the intervention. The study contributes to elucidating the association between SDB and HBP in pediatric patients. Moreover, it contributes to determining if intervention with adeno-tonsillectomy is associated with BP reduction. The results have direct implications for the management of SDB, providing essential information on treatment indications for existing clinical guidelines. NCT03696654. This work was supported by funds received by the ISCIII (PI18/00565 and PI22/01653), the Spanish Respiratory Society (Sociedad Española de Neumología y Cirugía Torácica- SEPAR) (535-2018 and 1073-2020), unconditioned research grant from Menarini Laboratories and NEUMOMADRID (Sociedad Madrileña de Neumología y Cirugía Torácica). Sleep-disordered breathing High blood pressure Sleep apnea Children Cardiovascular risk Adeno-tonsillectomy Prevalence of High Blood Pressure in Pediatric Patients with Sleep-Disordered Breathing, Reversibility after Treatment: The KIDS TRIAL Study Protocol