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               <dc:title>Body Skin laxity treatment using hybrid cooperative complexes of hyaluronans: a real-world data evaluation of patient-reported satisfaction</dc:title>
               <dc:creator>Margara, Andrea</dc:creator>
               <dc:creator>Siquier-Dameto, Gabriel</dc:creator>
               <dc:creator>Dell'Avanzato, Roberto</dc:creator>
               <dc:creator>Cigni, Clara</dc:creator>
               <dc:creator>Grimolizzi, Franco</dc:creator>
               <dc:creator>Bellia, Gilberto</dc:creator>
               <dc:subject>Cirurgia plàstica</dc:subject>
               <dc:subject>Plastic surgery</dc:subject>
               <dc:subject>Pell -- Cura i higiene</dc:subject>
               <dc:subject>Skin -- Care and hygiene</dc:subject>
               <dc:description>Background: The Profhilo® Body Kit is indicated for the treatment of skin laxity of the body and consists of the Profhilo® Body hyaluronic acid (HA) injectable, the HA-containing Profhilo® Figura Body Patch and the Profhilo® Figura Body Cream. Aim: To assess real-world data of patient-reported satisfaction associated with the Profhilo® Body Kit treatment for skin laxity of the inner arms, abdomen, décolleté, and knees. Methods: The Profhilo® Body injection and Profhilo® Figura Body Patch were administered on Day 0 and Day 30; the Profhilo® Figura Body Cream was applied daily between the two injections. Surveys were conducted using a web app tool (Day 0, Day 30 and 30-days after second injection) and assessed patient discomfort (Visual Analogue Scale), treatment effectiveness, and psychological and social function (effects assessed using four categories: 'not at all', 'a little', 'a lot' and 'very much'). Results: Patients (N=50; 83% female) were treated at centres in Italy (n=35) and in the Netherlands (n=15). Most patients had no/mild procedure-related pain (86%) and the majority of post-injection symptoms disappeared within 48 hours (94%). Over 80% of patients reported that treatment benefited them 'a lot' and 'very much', with improvements in skin laxity, skin hydration and skin firmness/tone; beneficial treatment effects were also reported for enhancement of body image, appearance and improvement in relationships. Discussion and Conclusions: These results indicate a high-level of patient-reported satisfaction due to the Profhilo® Body Kit and this contributes to the growing body of evidence supporting the use of Profhilo® Body for the treatment of skin laxity</dc:description>
               <dc:date>2025-02-27T20:32:20Z</dc:date>
               <dc:date>2025-02-27T20:32:20Z</dc:date>
               <dc:date>2024-08-19</dc:date>
               <dc:type>info:eu-repo/semantics/article</dc:type>
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               <dc:identifier>http://hdl.handle.net/10256/26480</dc:identifier>
               <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.29011/2574-7754.101937</dc:relation>
               <dc:relation>info:eu-repo/semantics/altIdentifier/issn/2574-7754</dc:relation>
               <dc:rights>Reconeixement-CompartirIgual 4.0 Internacional</dc:rights>
               <dc:rights>http://creativecommons.org/licenses/by-sa/4.0</dc:rights>
               <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
               <dc:publisher>Gavin Publishers</dc:publisher>
               <dc:source>Annals of Case Reports, 2024, vol. 9, núm. 4, p. 1-7</dc:source>
               <dc:source>Articles publicats (D-CM)</dc:source>
               <dc:source>Margara, Andrea Siquier-Dameto, Gabriel Dell'Avanzato, Roberto Cigni, Clara Grimolizzi, Franco Bellia, Gilberto 2024 Body Skin laxity treatment using hybrid cooperative complexes of hyaluronans: a real-world data evaluation of patient-reported satisfaction Annals of Case Reports 9 4 1 7</dc:source>
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