2026-04-17T16:57:23Zhttps://recercat.cat/oai/request

oai:recercat.cat:10256/252722024-10-29T21:04:42Zcom_2072_452955com_2072_2054col_2072_452961

2024-10-29T21:04:42Z urn:hdl:10256/25272 Increased salivary BDNF and improved fundamental motor skills in children following a 3-month integrated neuromuscular training in primary school Vasileva, Fidanka Font Lladó, Raquel Carreras Badosa, Gemma López Ros, Víctor Ferrusola-Pastrana, Anna López-Bermejo, Abel Prats Puig, Anna Motricitat Educació física Motor ability Physical education and training Infants -- Salut i higiene Children -- Health and hygiene Motricitat en els infants Motor ability in children Saliva Brain-derived neurotrophic factor (BDNF) is a protein involved in synaptic transmission and neuronal plasticity, which underlie learning and memory formation processes. Acute exercise and exercise training increases BDNF concentration. We aimed to evaluate the effects of a 3-month integrated neuromuscular training (INT) on salivary BDNF concentration and the mastery of fundamental motor skills in school-aged children. Another goal was to explore the associations between potential changes in BDNF and fundamental motor skills. Sixty-seven primary school-aged children were randomly allocated to control (N = 32; 7.52 ± 0.31 y) or INT groups (N = 35; 7.56 ± 0.29 y). A 3-month INT was applied during the warm-up of physical education (PE) classes, twice weekly. Salivary BDNF was measured using a sandwich-enzyme-linked immunosorbent assay and the mastery of fundamental motor skills was assessed using the CAMSA test, at baseline and after 3 months. The children in the INT group, as compared to the children in the control group, exhibited higher salivary BDNF (F = 8.865; p = 0.004), higher scores for sidestep (F = 13.240, p = 0.001), 1-foot hop (F = 11.684, p = 0.001), kick (F = 4.010, p = 0.050), the sum of locomotor skills (F = 18.799, p < 0.0001), and the sum of control and manipulative skills (F = 8.151, p = 0.006), as well as the total sum of fundamental motor skills (F = 11.266, p = 0.001) after the 3 months. Interestingly, the increase in salivary BDNF concentration after the 3-month INT was associated with an improvement in locomotor skills (beta = 0.385; p = 0.039; adjusted R2 = 0.088) and the total improvement in fundamental motor skills (beta = 0.428; p = 0.020; adjusted R2 = 0.124). A school-based 3-month INT increased salivary BDNF and improved the mastery of fundamental motor skills in children, highlighting the positive impact of this intervention on a pediatric population This research was funded by the Ministry of Science and Innovation (MCIN/AEI/484 10.13039/501100011033) and the “ERDF A way of making Europe”, funded by the European Union (PID2021-124162OA-I00). F.V. holds a fellowship from the Secretariat for Universities and Research of the Ministry of Business and Knowledge of the Government of Catalonia and the European Social Fund (2022FI_B1 00074). A.L.-B. is an investigator of the I3 Fund for Scientific Research (Ministry of Science and Innovation, Spain) 2024-10-29T21:04:42Z 2024-10-29T21:04:42Z 2024-08-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion peer-reviewed http://hdl.handle.net/10256/25272 info:eu-repo/semantics/altIdentifier/doi/10.3390/jfmk9030154 info:eu-repo/semantics/altIdentifier/issn/2411-5142 PID2021-124162OA-I00 info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2021-124162OA-I00/ES/CAMBIOS EN LA METILACION DEL ADN DE GENOMA COMPLETO EN SALIVA TRAS 3 MESES UNA INTERVENCION DE EJERCICIO FISICO EN ESCOLARES Y JUGADORES DE BALONCESTO/ Reconeixement 4.0 Internacional http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess MDPI (Multidisciplinary Digital Publishing Institute) Journal of Functional Morphology and Kinesiology, 2024, vol. 9, núm. 3, p. 154 Articles publicats (D-DE) Vasileva, Fidanka Font Lladó, Raquel Carreras Badosa, Gemma López Ros, Víctor Ferrusola-Pastrana, Anna López-Bermejo, Abel Prats Puig, Anna 2024 Increased salivary BDNF and improved fundamental motor skills in children following a 3-month integrated neuromuscular training in primary school Journal of Functional Morphology and Kinesiology 9 3 154