2026-04-13T02:02:47Zhttps://recercat.cat/oai/request
oai:recercat.cat:10256/251722024-10-29T16:14:21Zcom_2072_452955com_2072_2054col_2072_452960
RECERCAT author Vasileva, Fidanka author Carreras Badosa, Gemma author Bassols Casadevall, Judit author Serrano Ferrer, Juan author Font Lladó, Raquel author López Ros, Víctor author Osiniri Kippes, Inés author Martínez-Calcerrada, José María author San-Millán, Marta author López-Bermejo, Abel author Prats Puig, Anna 2024-10-29T16:14:21Z 2024-10-29T16:14:21Z 2024-03-20 http://hdl.handle.net/10256/25172 Background: Physical activity (PA) is beneficial for the overall health. Objectives are: (1) To compare metabolic (MRM) and cardiovascular-risk-markers (CRM) in children according to their PA-level; (2) to explore the associations of MRM and CRM with PA and sedentary time (ST); and (3) to identify the associations between MRM and CRM in less (LA) and more active (MA) children. Methods: A total of 238 apparently healthy school-aged children were enrolled (132 boys/106 girls; 9.1 ± 1.8 years) and body mass index standard deviation score (BMI SDS) and blood pressure were assessed. Fasting venous blood sampling was performed to assess insulin resistance (HOMA-IR) and high-sensitivity-C-reactive protein (hsCRP). Epicardial fat, interventricular septal and left ventricular posterior wall thicknesses were assessed by high-resolution ultrasonography. PA and ST were assessed by enKid-questionnaire. Children were classified based on enKid-score as being LA and MA (below and above 50th percentile for PA). Results: MA-children had lower values for: BMI SDS, diastolic-to-systolic blood pressure ratio, HOMA-IR and hsCRP (7.02 to 61.5% lower, p = 0.040 to p < 0.0001) compared to LA-children. MRM and CRM were positively associated with ST (p = 0.003 to p < 0.001), and negatively associated with PA (p = 0.044 to p < 0.001). Finally, MRM were positively associated with CRM (p = 0.008 to p < 0.0001). Interestingly, the latter associations were observed in LA-children but were not present in MA-children. Conclusion: More PA is associated with better cardio-metabolic profile in school-aged children. PA seems to modulate the associations between MRM and CRM, thus reinforcing the idea that fostering PA in children may lower the risk for development of a cardio-metabolic disease Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess Greix -- Metabolisme Fat -- Metabolism Sedentarisme Sedentary behavior Insulin resistance, C-reactive protein, diastolic to systolic blood pressure ratio and epicardial fat are related to sedentary time, and inversely related to physical activity in school-aged children info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion peer-reviewed