2026-04-17T07:54:00Zhttps://recercat.cat/oai/request

oai:recercat.cat:10256/251722024-10-29T16:14:21Zcom_2072_452955com_2072_2054col_2072_452960

2024-10-29T16:14:21Z urn:hdl:10256/25172 Insulin resistance, C-reactive protein, diastolic to systolic blood pressure ratio and epicardial fat are related to sedentary time, and inversely related to physical activity in school-aged children Vasileva, Fidanka Carreras Badosa, Gemma Bassols Casadevall, Judit Serrano Ferrer, Juan Font Lladó, Raquel López Ros, Víctor Osiniri Kippes, Inés Martínez-Calcerrada, José María San-Millán, Marta López-Bermejo, Abel Prats Puig, Anna Greix -- Metabolisme Fat -- Metabolism Sedentarisme Sedentary behavior Background: Physical activity (PA) is beneficial for the overall health. Objectives are: (1) To compare metabolic (MRM) and cardiovascular-risk-markers (CRM) in children according to their PA-level; (2) to explore the associations of MRM and CRM with PA and sedentary time (ST); and (3) to identify the associations between MRM and CRM in less (LA) and more active (MA) children. Methods: A total of 238 apparently healthy school-aged children were enrolled (132 boys/106 girls; 9.1 ± 1.8 years) and body mass index standard deviation score (BMI SDS) and blood pressure were assessed. Fasting venous blood sampling was performed to assess insulin resistance (HOMA-IR) and high-sensitivity-C-reactive protein (hsCRP). Epicardial fat, interventricular septal and left ventricular posterior wall thicknesses were assessed by high-resolution ultrasonography. PA and ST were assessed by enKid-questionnaire. Children were classified based on enKid-score as being LA and MA (below and above 50th percentile for PA). Results: MA-children had lower values for: BMI SDS, diastolic-to-systolic blood pressure ratio, HOMA-IR and hsCRP (7.02 to 61.5% lower, p = 0.040 to p < 0.0001) compared to LA-children. MRM and CRM were positively associated with ST (p = 0.003 to p < 0.001), and negatively associated with PA (p = 0.044 to p < 0.001). Finally, MRM were positively associated with CRM (p = 0.008 to p < 0.0001). Interestingly, the latter associations were observed in LA-children but were not present in MA-children. Conclusion: More PA is associated with better cardio-metabolic profile in school-aged children. PA seems to modulate the associations between MRM and CRM, thus reinforcing the idea that fostering PA in children may lower the risk for development of a cardio-metabolic disease 2024-10-29T16:14:21Z 2024-10-29T16:14:21Z 2024-03-20 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion peer-reviewed http://hdl.handle.net/10256/25172 info:eu-repo/semantics/altIdentifier/doi/10.3389/fpubh.2024.1339860 info:eu-repo/semantics/altIdentifier/eissn/2296-2565 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess Frontiers Media Frontiers in Public Health, 2024, vol. 12, art. núm. 1339860 Articles publicats (D-CM)