2026-04-18T05:57:11Zhttps://recercat.cat/oai/request

oai:recercat.cat:10256/250512025-02-03T08:40:02Zcom_2072_452955com_2072_2054col_2072_452960

00925njm 22002777a 4500 dc Siquier-Dameto, Gabriel author Boadas i Vaello, Pere author Verdú Navarro, Enrique author 2024-06-26 Intradermal injection of bioactive compounds is used to reduce the effects of aging skin. The aim of this work is to study the response of facial injection of a hyaluronic acid complex supplemented with amino acids and antioxidant vitamins on skin rejuvenation. A total of 40 healthy adult subjects were recruited to whom this complex was injected into the facial skin, three consecutive times every two weeks. Together with assessing the degree of skin hydration, the level of skin microcirculation, wrinkles, skin color, and skin biomechanical parameters were evaluated. Using the GAIS scale, the degree of satisfaction of the participants was assessed. At 42 days (D42), there was an 11–12% increase in skin hydration and viscoelasticity, a 23% increase in skin density, a 27% increase in skin microcirculation, and a significant lightening and whitening of skin color, but without causing changes in skin wrinkles. A value between 1 and 3 on the GAIS scale was observed between 70 and 92% of the participants, and 87% of subjects found their skin more beautiful, 85% would recommend this treatment, and more than 50% found their face rejuvenated. In summary, the intradermal treatment tested suggests skin rejuvenation, with a good degree of safety Pell -- Envelliment Skin -- Aging Pell -- Cura i higiene Skin -- Care and hygiene Antioxidants Mesoteràpia Mesotherapy Medicina estètica Aesthetic medicine Intradermal Treatment with a Hyaluronic Acid Complex Supplemented with Amino Acids and Antioxidant Vitamins Improves Cutaneous Hydration and Viscoelasticity in Healthy Subjects