2026-04-17T14:39:29Zhttps://recercat.cat/oai/requestoai:recercat.cat:10256/181472024-05-21T10:37:25Zcom_2072_452955com_2072_2054col_2072_452960
RECERCAT
author
Gómez Marcos, Manuel A.
author
Gómez Sánchez, Leticia
author
Patino Alonso, Maria Carmen
author
Recio Rodriguez, Jose I.
author
Gómez Sánchez, Marta
author
Rigo, Fernando
author
Martí Lluch, Ruth
author
Agudo Conde, Cristina
author
Maderuelo Fernández, José A.
author
Ramos Blanes, Rafel
author
García Ortiz, Luís
author
Rodríguez Sánchez, Emiliano
2024-05-21T10:37:25Z
2024-05-21T10:37:25Z
2019-01-25
http://hdl.handle.net/10256/18147
Background
Obesity increases mortality, and is linked to cardiovascular diseases and metabolic syndrome (MetS). Therefore, the purpose of this study was to analyze the ability of different adiposity indices to identify subjects with MetS among people with intermediate cariovascular
risk.
Materials and methods
The cross-sectional study involved 2478 subjects, recruited by the MARK study. Adiposity
measures: general adiposity by body mass index (BMI), central adiposity by waist-to-height
ratio (WHtR), fat mass percent by the Clı´nica Universidad de Navarra—body adiposity estimator (CUN-BAE), percentage of body fat and of visceral adipose tissue by body roundness
index (BRI) and visceral obesity and general adiposity with body shape index (ABSI). The
diagnosis of MetS was made in accordance with the criteria established in the international
consensus of the Joint Scientific Statement National Cholesterol Education Program III.
Results
The highest correlation coefficients were obtained by the glycemic components (HbA1c and
FPG) of the MetS and ranged from 0.155 to 0.320. The exception was ABSI, which showed
lower values in the global analysis and in the males. Values of the area under the ROC
curve with the adiposity indices ranged from 0.773 with the BMI in males to 0.567 with ABSI in males. In the logistic regression analysis, all adiposity factors, except ABSI, showed similar OR values of MetS after adjusting for possible confounding factors. In the global analysis,
the adiposity index that showed a highest OR of MetS was CUN-BAE (OR 5.50; 95% CI
4.27–7.09). In the analysis by gender, the highest ORs were BMI in males (OR 5.98; 95% CI
4.70–7.60) and both WHtR and BRI in females (OR 4.15; 95% CI 3.09–5.58).
Conclusion
All adiposity indices, except for ABSI, show an association with MetS and similar ability to
detect subjects with MetS among people with intermediate cariovascular riskThis work was supported by grants from
the Spanish Ministry of Science and Innovation
(MICINN), the Carlos III Health Institute/European
Regional Development Fund (ERDF) (MICINN,
ISCIII/FEDER) (Red RedIAPP RD06/0018,
Research Groups: RD16/0007/0003, RD16/0007/
0004, RD16/0007/0008), the Health Research Fund (PI10/01088, PI10/02077, PI10/02043; PI13/
01930), and the Regional Health Management of
Castile and Leo´n (GRS 635/A/11; GRS 906/B/14
Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess
Obesitat
Obesity
Sistema cardiovascular -- Malalties
Cardiovascular system -- Diseases
Capacity adiposity indices to identify metabolic syndrome in subjects with intermediate cardiovascular risk (MARK study)
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion peer-reviewed