2026-04-13T04:50:09Zhttps://recercat.cat/oai/request

oai:recercat.cat:10230/729102026-03-27T20:38:26Zcom_2072_6col_2072_452952

00925njm 22002777a 4500 dc Shyam, Sangeetha author Babio, Nancy author Paz-Graniel, Indira author Martínez-González, Miguel Ángel, 1957- author Sorlí, José Vicente author Estruch, Ramón author Ros, Emilio author Tojal Sierra, Lucas author Gómez-Gracia, Enrique author Fiol, Miquel author Lapetra, José author Serra Majem, Lluís author Riera-Mestre, Antoni author Toledo, Estefania author Ramirez-Sabio, Judith B author Castañer, Olga author Lamuela-Raventós, Rosa M. author Margara Escudero, Hernando J. author Fitó Colomer, Montserrat author Salas-Salvadó, Jordi author 2026-03-26T11:06:44Z 2026-03-26T11:06:44Z 2025 2026-03-26T11:06:44Z The food system is a key determinant of population and planetary health. As the "one planet, one health" approach gains momentum, evaluating "food biodiversity" and its association with mortality in high-risks populations is increasingly important. Hence, we evaluated the associations of food biodiversity with all-cause and cause-specific mortality in a Spanish cohort of older adults at high cardiovascular risks. Food biodiversity was defined using dietary species richness (DSR), the count of unique plants and animal species consumed by an individual. DSR was cumulatively calculated over the PREDIMED study follow-up, using yearly food frequency questionnaire data. The association of food biodiversity with all-cause and cause-specific mortality was assessed using Cox regression, while controlling for confounders. We analyzed data from 7210 participants (58 % women), with a median age of 67 years. DSR in the cohort ranged between 16 and 57 (median: 48). Over a median follow-up of 6 years, 425 deaths were recorded (103 deaths from cardiovascular diseases (CVD), 169 cancer deaths, and 153 deaths due to other-causes). DSR was only moderately correlated with adherence to the Mediterranean diet. On average, when fully adjusted, every additional species over the follow-up period was associated with a Hazard Ratio (HR (95 % Confidence Interval) of 0.91(0.90,0.93) for all-cause mortality, 0.93(0.90,0.96) for CVD mortality, 0.92 (0.89,0.94) for cancer deaths, and a 0.91(0.89,0.94) for deaths from other causes. Dietary recommendations to improve food biodiversity may increase longevity. Supported by Instituto de Salud Carlos III, Spanish Ministry of Health, through grants provided to research networks specifically developed for the study (RTIC G03/140, to Dr. Estruch, and RTIC RD 06/0045, to Dr. Martínez-González); Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición; and grants from Centro Nacional de Investigaciones Cardiovasculares (CNIC 06/2007), Fondo de Investigación Sanitaria-Fondo Europeo de Desarrollo Regional (PI04-2239, PI 05/2584, CP06/00100, PI07/0240, PI07/1138, PI07/0954, PI 07/0473, PI10/01407, PI10/02658, PI11/01647, and P11/02505), Ministerio de Ciencia e Innovación (AGL-2009-13906-C02 and AGL2010-22319-C03), Fundación Mapfre 2010, Consejería de Salud de la Junta de Andalucía (PI0105/2007), Public Health Division of the Department of Health of the Autonomous Government of Catalonia, Generalitat Valenciana (ACOMP06109, GVACOMP2010-181, GVACOMP2011-151, CS2010-AP-111, and CS2011-AP-042), and Regional Government of Navarra (P27/2011). https://hdl.handle.net/10230/72910 Food biodiversity Mediterranean diet Mortality Older adults Food biodiversity and mortality in older Mediterranean adults with high cardiovascular risk