2026-04-14T05:08:42Zhttps://recercat.cat/oai/requestoai:recercat.cat:10230/591072025-12-12T02:07:46Zcom_2072_6col_2072_452952
RECERCAT
author
Salgado, Heladia
author
Gelpí, Josep Lluís
author
Collado Vides, Pedro Julio
2024-02-14T10:58:07Z2024-02-14T10:58:07Z2024
RegulonDB is a database that contains the most comprehensive corpus of knowledge of the regulation of transcription initiation of Escherichia coli K-12, including data from both classical molecular biology and high-throughput methodologies. Here, we describe biological advances since our last NAR paper of 2019. We explain the changes to satisfy FAIR requirements. We also present a full reconstruction of the RegulonDB computational infrastructure, which has significantly improved data storage, retrieval and accessibility and thus supports a more intuitive and user-friendly experience. The integration of graphical tools provides clear visual representations of genetic regulation data, facilitating data interpretation and knowledge integration. RegulonDB version 12.0 can be accessed at https://regulondb.ccg.unam.mx.
© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com http://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess
Biologia molecular
Regulació genètica
RegulonDB v12.0: a comprehensive resource of transcriptional regulation in E. coli K-12
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion