2026-04-14T04:49:50Zhttps://recercat.cat/oai/request

oai:recercat.cat:10230/591072025-12-12T02:07:46Zcom_2072_6col_2072_452952

00925njm 22002777a 4500 dc Salgado, Heladia author Gelpí, Josep Lluís author Collado Vides, Pedro Julio author 2024-02-14T10:58:07Z 2024-02-14T10:58:07Z 2024 RegulonDB is a database that contains the most comprehensive corpus of knowledge of the regulation of transcription initiation of Escherichia coli K-12, including data from both classical molecular biology and high-throughput methodologies. Here, we describe biological advances since our last NAR paper of 2019. We explain the changes to satisfy FAIR requirements. We also present a full reconstruction of the RegulonDB computational infrastructure, which has significantly improved data storage, retrieval and accessibility and thus supports a more intuitive and user-friendly experience. The integration of graphical tools provides clear visual representations of genetic regulation data, facilitating data interpretation and knowledge integration. RegulonDB version 12.0 can be accessed at https://regulondb.ccg.unam.mx. Biologia molecular Regulació genètica RegulonDB v12.0: a comprehensive resource of transcriptional regulation in E. coli K-12