2026-04-14T04:40:56Zhttps://recercat.cat/oai/request

oai:recercat.cat:10230/572032025-12-12T01:53:42Zcom_2072_6col_2072_452952

00925njm 22002777a 4500 dc Buekers, Joren author Arbillaga Etxarri, Ane, 1986- author Gimeno Santos, Elena, 1980- author Donaire González, David author Chevance, Guillaume author Aerts, Jean-Marie author García Aymerich, Judith author 2023-06-19T05:53:25Z 2023-06-19T05:53:25Z 2023 Continuous physiological measurements during a laboratory-based exercise test can provide physiological biomarkers, such as heart rate (HR) and oxygen uptake (V̇O2) kinetics, that carry clinically relevant information. In contrast, it is not clear how continuous data generated by wearable devices during daily-life routines could provide meaningful biomarkers. We aimed to determine whether valid HR and V̇O2 kinetics can be obtained from measurements with wearable devices during outdoor walks in patients with chronic obstructive pulmonary disease (COPD). HR (Polar Belt) and V̇O2(METAMAX3B) were measured during 93 physical activity transitions performed by eight patients with COPD during three different outdoor walks (ntr = 77) and a 6-minute walk test (ntr = 16). HR and V̇O2 kinetics were calculated every time a participant started a walk, finished a walk or walked upstairs. HR and V̇O2 kinetics were considered valid if the response magnitude and model fit were adequate, and model parameters were reliable. Continuous measurements with wearable devices provided valid HR kinetics when COPD patients started or finished (range 63%–100%) the different outdoor walks and valid V̇O2 kinetics when they finished (range 63%–100%) an outdoor walk. The amount of valid kinetics and kinetic model performance was comparable between outdoor walks and a laboratory-based exercise test (p > .05). We envision that the presented approach could improve telemonitoring applications of patients with COPD by providing regular, unsupervised assessments of HR kinetics during daily-life routines. This could allow to early identify a decline in the patients’ dynamic physiological functioning, physical fitness and/or health status. Joren Buekers acknowledges the support of the European Respiratory Society – ERS Long-Term Research Fellowship 2020. ISGlobal acknowledges support from the Spanish Ministry of Science and Innovation through the ‘Centro de Excelencia Severo Ochoa 2019–2023’ Program (CEX2018-000806-S) and support from the Generalitat de Catalunya through the CERCA Program. Respiratory medicine Wearables personalised medicine mHealth physiology Remote patient monitoring personalised medicine Exercise lifestyle Telehealth general Heart rate and oxygen uptake kinetics obtained from continuous measurements with wearable devices during outdoor walks of patients with COPD