2026-04-17T07:56:02Zhttps://recercat.cat/oai/request

oai:recercat.cat:10230/448242025-12-20T16:59:30Zcom_2072_6col_2072_452952

00925njm 22002777a 4500 dc Storås, Anne Holck author Sanda, Martin George author Garin Boronat, Olatz, 1979- author Chang, Peter author Patil, Dattatraya author Crociani, Catrina M. author Suárez Novo, José Francisco author Cvancarova, Milada author Loge, Jon Håvard author Fosså, Sophie D. author 2020-05-27T07:11:23Z 2020-05-27T07:11:23Z 2020 Objective: To compare pre- and post-radical prostatectomy (RP) responses in the urinary incontinence domain of Expanded Prostate Cancer Index Composite-26 (EPIC-26) in cohorts from the USA, Norway and Spain. Methods: A prospective study of pre- and 1-year post-treatment responses in American (n=537), Norwegian (n=520) and Spanish (n=111) patients, establishing the prevalence of urinary incontinence defined according to published dichotomization. Thereafter we focused on the response alternatives "occasional dribbling", pad use and problem experience. A multivariate logistic regression analysis (significance level ≤ 0.01) considered risk factors for "not retaining total control". Results: Compared to the European men, the American patients were younger, healthier and more presented with lower risk tumors. Before RP no inter-country differences emerged the prevalence of urinary incontinence (6%). One-year post-treatment urinary incontinence was described by 30% of the American and 41% of the European patients, occasional dribbling being the most frequent type of urinary leakage. In the multivariate analysis the risk of "not retaining total control" increased almost 3-fold in European compared to American patients, with age and co-morbidity being additional independent risk factor. Conclusion: After RP patients from Spain and Norway reported more unfavorable outcomes by EPIC-26 than the American patients to most of the urinary incontinence items, the difference between the European and American patients remaining in the multivariate analysis. The most frequent post-RP response alternative "occasional dribbling" needs to be validated with pad weighing as "gold standard". Adverse effects Prostate cancer Radical prostatectomy Urinary incontinence A prospective study of patient reported urinary incontinence among American, Norwegian and Spanish men 1 year after prostatectomy