2026-04-17T15:55:37Zhttps://recercat.cat/oai/request
oai:recercat.cat:10230/259442026-02-04T18:00:13Zcom_2072_6col_2072_452952
RECERCAT author Grau Sanmartí, Núria, 1974- author Bazán, Víctor author Kallouchi, Mohamed author Rodríguez, Diego author Estirado Vera, Cristina, 1968- author Corral Celma, María Isabel author Valls Córdoba, Maria Teresa author Ramos Ardanaz, Pablo author Sanjuas, Carles author Félez Flor, Miguel Ángel author Vallés Gras, Ermengol author Benito Villabriga, Begoña author Gea Guiral, Joaquim author Bruguera-Cortada, Jordi author Martí-Almor, Julio 2016-02-25T09:50:05Z2017-01-31T03:00:05Z2016 INTRODUCTION: Autonomic dysfunction can alter heart rate variability and increase the incidence of arrhythmia. We analyzed the impact of continuous positive airway pressure (CPAP) on this pathophysiological phenomenon in patients with severe sleep apnea-hypopnea syndrome. METHODS: Consecutive patients with recently diagnosed severe sleep apnea-hypopnea syndrome were prospectively considered for inclusion. Incidence of arrhythmia and heart rate variability (recorded on a 24-hour Holter monitoring device) were analyzed before starting CPAP therapy and 1 year thereafter. RESULTS: A total of 26 patients were included in the study. CPAP was administered for 6.6±1.8hours during Holter monitoring. After starting CPAP, we observed a marginally significant reduction in mean HR (80±9 to 77±11 bpm, p=.05). CPAP was associated with partial modulation (only during waking hours) of r-MSSD (p=.047) and HF (p=.025) parasympathetic parameters and LF (p=.049) sympathetic modulation parameters. None of these parameters returned completely to normal levels (p<.001). The number of unsustained episodes of atrial tachycardia diminished (p=.024), but no clear effect on other arrhythmias was observed. CONCLUSIONS: CPAP therapy only partially improves heart rate variability, and exclusively during waking hours, and reduces incidence of atrial tachycardia, both of which can influence cardiovascular morbidity and mortality in sleep apnea-hypopnea syndrome patients. © Copyright 2016. Grau N, Bazan V, Kallouchi M, Rodriguez D, Estirado C, Corral MI. et al. Long-term Impact of Continuous Positive Airway Pressure Therapy on Arrhythmia and Heart Rate Variability in Patients With Sleep Apnea. Arch Bronconeumol. 2016 Jan;52(1):17-23. The definitive versión is available online at http://dx.doi.org/10.1016/j.arbres.2015.03.008 info:eu-repo/semantics/openAccess Arrítmia Cor -- Batecs Long-term Impact of Continuous Positive Airway Pressure Therapy on Arrhythmia and Heart Rate Variability in Patients With Sleep Apnea. info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion