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oai:recercat.cat:10230/231872025-12-22T13:40:10Zcom_2072_6col_2072_452952

00925njm 22002777a 4500 dc Solana, Rafael author Tarazona, Raquel author Aiello, Allison E. author Akbar, Arne N. author Appay, Victor author Beswick, Mark author Bosch, Jos A. author Campos, Carmen author Cantisán, Sara author Cicin Sain, Luca author Derhovanessian, Evelyna author Ferrando Martínez, Sara author Frasca, Daniela author Fulöp, Tamas author Govind, Sheila author Grubeck Loebenstein, Beatrix author Hill, Ann author Hurme, Mikko author Kern, Florian author Larbi, Anis author López-Botet, M. (Miguel) author Maier, Andrea B. author McElhaney, Janet E. author Moss, Paul author Naumova, Elissaveta author Nikolich Zugich, Janko author Pera, Alejandra author Rector, Jerrarld L. author Riddell, Natalie author Sanchez Correa, Beatriz author Sansoni, Paolo author Sauce, Delphine author Lier, Rene van author Wang, George C. author Wills, Mark R. author Zielinski, Maciej author Pawelec, Graham author 2015-03-16T08:16:24Z 2015-03-16T08:16:24Z 2012 Alone among herpesviruses, persistent Cytomegalovirus (CMV) markedly alters the numbers and proportions of peripheral immune cells in infected-vs-uninfected people. Because the rate of CMV infection increases with age in most countries, it has been suggested that it drives or at least exacerbates “immunosenescence”. This contention remains controversial and was the primary subject of the Third International Workshop on CMV & Immunosenescence which was held in Cordoba, Spain, 15-16th March, 2012. Discussions focused on several main themes including the effects of CMV on adaptive immunity and immunosenescence, characterization of CMV-specific T cells, impact of CMV infection and ageing on innate immunity, and finally, most important, the clinical implications of immunosenescence and CMV infection. Here we summarize the major findings of this workshop. The Workshop was partially supported by the University of Cordoba and the Spanish Ministry of Science (SAF2011-16169-E) Immunitat cel·lular CMV and Immunosenescence: from basics to clinics