dc.contributor.author |
malERA Refresh Consultative Panel on Tools for Malaria Elimination |
dc.contributor.author |
Rabinovich, Regina |
dc.date |
2018-02-07T12:35:25Z |
dc.date |
2018-02-07T12:35:25Z |
dc.date |
2017-11-30 |
dc.date |
2018-01-24T18:59:53Z |
dc.identifier.citation |
1549-1277 |
dc.identifier.uri |
http://hdl.handle.net/2445/119647 |
dc.format |
35 p. |
dc.format |
application/pdf |
dc.language.iso |
eng |
dc.publisher |
Public Library of Science (PLoS) |
dc.relation |
Reproducció del document publicat a:
http://dx.doi.org/10.1371/journal.pmed.1002455 |
dc.relation |
PLoS Medicine, 2017, vol. 14, num. 11, p. e1002455 |
dc.relation |
http://dx.doi.org/10.1371/journal.pmed.1002455 |
dc.rights |
cc by (c) malERA Refresh Consultative Panel on Tools for Malaria Elimination, 2017 |
dc.rights |
info:eu-repo/semantics/openAccess |
dc.rights |
http://creativecommons.org/licenses/by/3.0/es/ |
dc.subject |
Malària |
dc.subject |
Malalties parasitàries |
dc.subject |
Malaria |
dc.subject |
Parasitic diseases |
dc.title |
malERA: An updated research agenda for diagnostics, drugs,
vaccines, and vector control in malaria elimination and
eradication |
dc.type |
info:eu-repo/semantics/article |
dc.type |
info:eu-repo/semantics/publishedVersion |
dc.description.abstract |
Since the turn of the century, a remarkable expansion has been
achieved in the range and effectiveness of products and
strategies available to prevent, treat, and control malaria,
including advances in diagnostics, drugs, vaccines, and vector
control. These advances have once again put malaria elimination
on the agenda. However, it is clear that even with the means
available today, malaria control and elimination pose a
formidable challenge in many settings. Thus, currently available
resources must be used more effectively, and new products and
approaches likely to achieve these goals must be developed. This
paper considers tools (both those available and others that may
be required) to achieve and maintain malaria elimination. New
diagnostics are needed to direct treatment and detect
transmission potential; new drugs and vaccines to overcome
existing resistance and protect against clinical and severe
disease, as well as block transmission and prevent relapses; and
new vector control measures to overcome insecticide resistance
and more powerfully interrupt transmission. It is also essential
that strategies for combining new and existing approaches are
developed for different settings to maximise their longevity and
effectiveness in areas with continuing transmission and
receptivity. For areas where local elimination has been recently
achieved, understanding which measures are needed to maintain
elimination is necessary to prevent rebound and the
reestablishment of transmission. This becomes increasingly
important as more countries move towards elimination. |