Title:
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A new synthetic approach to the lactol moiety of halichoblelide
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Author:
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Santos, David; Ariza Piquer, Xavier; García Gómez, Jordi; Sánchez Zarzalejo, Carolina
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Other authors:
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Universitat de Barcelona |
Abstract:
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A stereoselective approach to the γ-lactol moiety of halichoblelide is described starting from commercially available (R)-1-butyn-3-ol. The key step is the hydroboration of a chiral protected 1,2-butadien-3-ol and its addition to furfural. |
Subject(s):
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-Síntesi orgànica -Aldehids -Organic synthesis -Aldehydes |
Rights:
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(c) Elsevier B.V., 2011
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Document type:
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Article Article - Accepted version |
Published by:
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Elsevier B.V.
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