Títol:
|
Dialkylammonium tert-Butylmethylphosphinites: Stable Intermediates for the Synthesis of P-Stereogenic Ligands
|
Autor/a:
|
Salomó, Ernest; Prades, Amparo; Riera i Escalé, Antoni; Verdaguer i Espaulella, Xavier
|
Altres autors:
|
Universitat de Barcelona |
Abstract:
|
The preparation of shelf-stable crystalline salts of tert-butylmethylphosphinous acid borane 1 is described. X-ray analysis of diisopropylammonium tert-butylmethylphosphinite borane 4 revealed the existence of a cyclic hydrogen-bond network in the solid state which accounts for the increased melting point and stability. Dialkylammonium phosphinite boranes are convenient precursors of the chiral tert-butylmethylphosphine fragment. Compound 4 can be directly employed in SN2@P reactions with different nucleophiles to yield valuable P-stereogenic intermediates and ligands. |
Matèries:
|
-Lligands (Bioquímica) -Compostos fosforosos -Catàlisi asimètrica -Ligands (Biochemistry) -Phosphorus compounds -Enantioselective catalysis |
Drets:
|
(c) American Chemical Society, 2017
|
Tipus de document:
|
Article Article - Versió acceptada |
Publicat per:
|
American Chemical Society
|
Compartir:
|
|