The antioxidant, antibacterial and anti-inflammatory activities, of the extract of the Narcissus broussonetii bulbs were studied. The report concerning those properties of this Moroccan endemic species is described for the first time. Nine main alkaloids compounds were identified by GC and GC-MS such as tazettine, pretazettine, homolycorine, lycorine, ismine, 3-epimacronine and papiramine. The extracts of N. broussonetii up to 40 mg/100g b.wt, revealed a significant anti-inflammatory effect in mice and showed also a significant scavenging activity at 10 mg mL-1 . However, the extract showed a moderate antibacterial activity against all the microorganisms tested.