Para acceder a los documentos con el texto completo, por favor, siga el siguiente enlace: http://hdl.handle.net/2445/101573

Rhinovirus Species and Clinical Features in Children Hospitalized with Pneumonia from Mozambique
Annamalay, A. A.; Lanaspa, Miguel; Khoo, S. K.; Madrid, Lola; Acácio, Sozinho; Zhang, G.; Laing, I.; Gern, J.; Goldblatt, J.; Bizzintino, J.; Lehmann, D.; Le Souef, P.N.; Bassat Orellana, Quique
OBJECTIVES: To describe the prevalence of human rhinovirus (RV) species in children hospitalized with pneumonia in Manhica, Mozambique; and the associations between RV species and demographic, clinical, and laboratory features. METHODS: Nasopharyngeal aspirates were collected from children 0-10 years of age (n=277) presenting to Manhica District Hospital with clinical pneumonia. Blood samples were collected for HIV and malaria testing, blood culture and full blood counts, and a chest X-ray was performed. A panel of common respiratory viruses was investigated using two independent multiplex RT-PCR assays with primers specific for each virus and viral type. RV species and genotypes were identified by semi-nested PCR assays, sequencing and phylogenetic tree analyses. RESULTS: At least one respiratory virus was identified in 206 (74.4%) children hospitalized with clinical pneumonia. RV was the most common virus identified in both HIV-infected (17/38, 44.7%) and HIV-uninfected (74/237, 31.2%; p=0.100) children. RV-A was the most common RV species identified (47/275, 17.0%), followed by RV-C (35/275, 12.6%) and RV-B (8/275, 2.9%). Clinical presentation of the different RV species was similar and overlapping, with no particular species being associated with specific clinical features. CONCLUSIONS: RV-A and RV-C were the most common respiratory viruses identified in children hospitalised with clinical pneumonia in Manhica. Clinical presentation of RV-A and RV-C was similar and overlapping. This article is protected by copyright. All rights reserved.
Pneumònia
Infants
Moçambic
Pneumonia
Children
Mozambique
(c) John Wiley & Sons, 2016
info:eu-repo/semantics/embargoedAccess
Artículo
info:eu-repo/semantics/acceptedVersion
John Wiley & Sons
         

Mostrar el registro completo del ítem

Documentos relacionados

Otros documentos del mismo autor/a

Madrid, Lola; Acácio, Sozinho; Nhampossa, Tacilta; Lanaspa, Miguel; Sitoe, A.; Maculuve, S. A.; Mucavele, H.; Quintó, Llorenç; Sigaúque, B.; Bassat Orellana, Quique
Bassat Orellana, Quique; Lanaspa, Miguel; Machevo, Sonia; O'Callaghan Gordo, Cristina; Madrid, Lola; Nhampossa, Tacilta; Acácio, Sozinho; Roca, A.; Alonso, Pedro
Lanaspa, Miguel; O'Callaghan Gordo, Cristina; Machevo, Sonia; Madrid, Lola; Nhampossa, Tacilta; Acácio, Sozinho; Horra, C. de la; Friaza, V.; Campano, E.; Alonso, Pedro; Calderon, E.; Roca, A.; Bassat Orellana, Quique
Madrid, Lola; Lanaspa, Miguel; Maculuve, S. A.; Bassat Orellana, Quique
Acácio, Sozinho; Verani, J. R.; Lanaspa, Miguel; Fairlie, T. A.; Nhampossa, Tacilta; Rupérez, Maria; Aide, P.; Plikaytis, B. D.; Sacoor, C.; Macete, Eusébio; Alonso, Pedro; Sigaúque, B.