Molecular characterization of Streptococcus pneumoniae invasive serotype 19A isolates from adults in two Spanish regions (1994-2009)

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RECERCAT Home > Universitat de Barcelona > Patologia i Terapèutica Experimental > Articles publicats en revistes (Patologia i Terapèutica Experimental) > View document

To access the full text documents, please follow this link: http://hdl.handle.net/2445/99082

dc.contributor	Universitat de Barcelona
dc.contributor.author	Marimón, José María
dc.contributor.author	Alonso, Marta
dc.contributor.author	Rolo, D.
dc.contributor.author	Ardanuy Tisaire, María Carmen
dc.contributor.author	Liñares Louzao, Josefina
dc.contributor.author	Pérez Trallero, Emilio
dc.date	2016-05-31T11:26:02Z
dc.date	2016-05-31T11:26:02Z
dc.date	2012-06
dc.date	2016-05-31T11:26:07Z
dc.identifier.citation	0934-9723
dc.identifier.citation	615313
dc.identifier.uri	http://hdl.handle.net/2445/99082
dc.format	5 p.
dc.format	application/pdf
dc.language.iso	eng
dc.publisher	Springer Verlag
dc.relation	Versió postprint del document publicat a: http://dx.doi.org/10.1007/s10096-011-1399-3
dc.relation	European Journal of Clinical Microbiology & Infectious Diseases, 2012, vol. 31, num. 6, p. 1009-1013
dc.relation	http://dx.doi.org/10.1007/s10096-011-1399-3
dc.rights	(c) Springer Verlag, 2012
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	Estreptococs
dc.subject	Pneumococs
dc.subject	Infeccions per pneumococs
dc.subject	Vacuna antipneumocòccica
dc.subject	Resistència als medicaments
dc.subject	Barcelona (Catalunya : Província)
dc.subject	Sant Sebastià (País Basc)
dc.subject	Espanya
dc.subject	Streptococcus
dc.subject	Streptococcus pneumonia
dc.subject	Pneumococcal Infections
dc.subject	Pneumococcal vaccine
dc.subject	Drug resistance
dc.subject	Barcelona (Catalonia : Province)
dc.subject	San Sebastián (Basque Country)
dc.subject	Spain
dc.title	Molecular characterization of Streptococcus pneumoniae invasive serotype 19A isolates from adults in two Spanish regions (1994-2009)
dc.type	info:eu-repo/semantics/article
dc.type	info:eu-repo/semantics/acceptedVersion
dc.description.abstract	From 1994 to 2009, the incidence of invasive serotype 19A pneumococci isolated from adults in Barcelona and San Sebastian almost doubled every 4 years. Genotyping of the 167 invasive isolates studied showed serotype 19A to be highly heterogeneous, with 35 different sequence types (STs) and a different clonal structure in each region and time period. Multiresistance, defined as non-susceptibility to three or more antimicrobials, was found in 86 (51.5%) isolates. The most frequent ST was the multidrug-resistant ST276 (n = 28), which is a single-locus variant of the Denmark14-ST230 global clone. The ST276 clone, only present in San Sebastian before 2001, was successfully disseminated from 2002 in both cities and was the main contributor to the overall increase of serotype 19A infections.

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