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Low prevalence of Cfr-mediated linezolid resistance among methicillin-resistant Staphylococcus aureus in a Spanish hospital: case report on linezolid resistance acquired during linezolid therapy
Sierra, Josep M.; Camoez, Mariana; Tubau, Fe; Gasch, Oriol; Pujol Rojo, Miquel; Martin, Rogelio; Domínguez Luzón, Ma. Ángeles (María Ángeles)
Universitat de Barcelona
Linezolid is an effective antimicrobial agent to treat methicillin-resistant Staphylococcus aureus (MRSA). Resistance to linezolid due to the cfr gene is described worldwide. The present study aimed to analyze the prevalence of the cfr-mediated linezolid resistance among MRSA clinical isolates in our area. A very low prevalence of cfr mediated linezolid resistance was found: only one bacteremic isolate out of 2 215 screened isolates. The only linezolid resistant isolate arose in a patient, previously colonized by MRSA, following linezolid therapy. Despite the low rate of resistance in our area, ongoing surveillance is advisable to avoid the spread of linezolid resistance.
Staphylococcus aureus
Unitats de cures intensives
Infeccions respiratòries
Staphylococcus aureus
Intensive care units
Respiratory infections
cc-by (c) Sierra, J.M. et al., 2013
http://creativecommons.org/licenses/by/3.0/es
Artículo
info:eu-repo/semantics/publishedVersion
Public Library of Science (PLoS)
         

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