The increasing deployment of distributed generation (DG) such as photovoltaic panels (PV) connected to low-voltage (LV) grids is becoming a common trend in urban areas. The advances of information and communication technology (ICT) facilitates the collaborative operation of DG systems to achieve collective benefits. The fusion of these two trends creates a new scenario where reactive power control methods can offer additional features and benefits beyond the conventional voltage regulation provided by the droop method. Taking advantage of this new scenario, this paper formulates the application of reactive power control as an optimization problem where simple and ideal settings are imposed by design in order to facilitate the exploration search as well as to avoid over-constraining the optimization space. By appropriately using the reactive power capacity of inverters, the desired collective benefit is to minimize power losses while individual voltages at each inverter should be kept within the statutory limits. The simulated solution of the optimization problem is applied to a real-inspired PV-LV grid subject to an over-voltage situation, which may typically occur during periods of high production but low consumption. Simulation results reveal unexpected optimal settings for reactive power control set-points at each inverter, which calls for a final discussion to review the applicability of the optimization approach.