Autor/a:
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Lorenzoni, Cesaltina; Vilajeliu, Alba; Carrilho, Carla; Ismail, Mamudo R.; Castillo, Paola; Augusto, Orvalho; García-Basteiro, Alberto L.; Sidat, Mohsin; Sanjosé Llongueras, Silvia de; Menéndez, Clara; Ordi i Majà, Jaume
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Abstract:
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BACKGROUND: Very limited information is available regarding the
incidence of cancer in sub-Saharan Africa. We analyzed changes
in cancer patterns from 1991 to 2008 in Maputo (Mozambique).
METHODS: We calculated the rates of incidence of different
cancer sites by sex in the 5-year age-group of the population of
Maputo city as well as age-standardized rates (ASRs) and average
annual percentage changes (AAPC). RESULTS: Over the 18-year
study period a total of 12,674 cases of cancer (56.9% females)
were registered with an overall increase in the risk of cancer
in both sexes. In males, the most common cancers were those of
the prostate, Kaposi sarcoma (KS) and the liver. Prostate cancer
showed the most dramatic increase over the whole study period
(AAPC +11.3%; 95% CI: 9.7-13.0), with an ASR of 61.7 per 105 in
2003-2008. In females, the most frequent cancers were of the
uterine cervix, the breast and KS, with the former increasing
along the whole study period (AAPC + 4.7%; 95% CI: 3.4-6) with
an ASR of 62.0 per 105 in 2003-2008 as well as breast cancer
(AAPC +6.5%; 95%CI: 4.3-8.7). CONCLUSIONS: Overall, the risk of
cancer rose in both sexes during the study period, particularly
among cancers associated with westernization of lifestyles
(prostate, breast), combined with increasingly rising incidences
or limited changes in cancers associated with infection and
poverty (uterine cervix, liver). Moreover, the burden of
AIDS-associated cancers has shown a marked increase. |