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Effect of the Mediterranean diet on blood pressure in the PREDIMED trial: results from a randomized controlled trial
Toledo, Estefanía; Hu, F. B.; Estruch Riba, Ramon; Buil-Cosiales, P.; Corella Piquer, Dolores; Salas Salvadó, Jordi; Covas Planells, María Isabel; Arós, Fernando; Gómez-Gracia, E.; Fiol Sala, Miguel; Lapetra, José; Serra Majem, Lluís; Pintó Sala, Xavier; Lamuela Raventós, Rosa Ma.; Sáez Tormo, Guillermo; Bulló, Mònica; Ruiz-Gutiérrez, Valentina; Ros Rahola, Emilio; Sorlí, J. V.; Martínez-González, Miguel Ángel, 1957-
Background: Hypertension can be prevented by adopting healthy dietary patterns. Our aim was to assess the 4-year effect on blood pressure (BP) control of a randomized feeding trial promoting the traditional Mediterranean dietary pattern. Methods: The PREDIMED primary prevention trial is a randomized, single-blinded, controlled trial conducted in Spanish primary healthcare centers. We recruited 7,447 men (aged 55 to 80 years) and women (aged 60 to 80 years) who had high risk for cardiovascular disease. Participants were assigned to a control group or to one of two Mediterranean diets. The control group received education on following a low-fat diet, while the groups on Mediterranean diets received nutritional education and also free foods; either extra virgin olive oil, or nuts. Trained personnel measured participants' BP at baseline and once yearly during a 4-year follow-up. We used generalized estimating equations to assess the differences between groups during the follow-up. Results: The percentage of participants with controlled BP increased in all three intervention groups (P-value for within-group changes: P<0.001). Participants allocated to either of the two Mediterranean diet groups had significantly lower diastolic BP than the participants in the control group (−1.53 mmHg (95% confidence interval (CI) −2.01 to −1.04) for the Mediterranean diet supplemented with extra virgin olive oil, and −0.65 mmHg (95% CI -1.15 to −0.15) mmHg for the Mediterranean diet supplemented with nuts). No between-group differences in changes of systolic BP were seen. Conclusions: Both the traditional Mediterranean diet and a low-fat diet exerted beneficial effects on BP and could be part of advice to patients for controlling BP. However, we found lower values of diastolic BP in the two groups promoting the Mediterranean diet with extra virgin olive oil or with nuts than in the control group.
Cuina mediterrània
Dieta
Pressió sanguínia
Malalties cardiovasculars
Mediterranean cooking
Diet
Blood pressure
Cardiovascular diseases
cc-by (c) BioMed Central, 2013
http://creativecommons.org/licenses/by/3.0/es
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BioMed Central
         

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Toledo, Estefanía; Hu, F. B.; Estruch Riba, Ramon; Buil-Cosiales, P.; Corella Piquer, Dolores; Salas Salvadó, Jordi; Covas Planells, María Isabel; Arós, Fernando; Gómez-Gracia, E.; Fiol Sala, Miguel; Lapetra, José; Serra Majem, Lluís; Pintó Sala, Xavier; Lamuela Raventós, Rosa Ma.; Sáez Tormo, Guillermo; Bulló, Mònica; Ruiz-Gutiérrez, Valentina; Ros Rahola, Emilio; Sorlí, J. V.; Martínez-González, Miguel Ángel, 1957-
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Estruch Riba, Ramon; Ros Rahola, Emilio; Salas Salvadó, Jordi; Covas Planells, María Isabel; Corella Piquer, Dolores; Arós, Fernando; Gómez-Gracia, E.; Ruiz-Gutiérrez, Valentina; Fiol Sala, Miguel; Lapetra, José; Lamuela Raventós, Rosa Ma.; Serra Majem, Lluís; Pintó Sala, Xavier; Basora-Gallisá, Josep; Muñoz, Miguel Ángel; Sorlí, J. V.; Martínez, J. A.; Martínez-González, Miguel Ángel, 1957-
Estruch Riba, Ramon; Ros Rahola, Emilio; Salas Salvadó, Jordi; Covas Planells, María Isabel; Corella Piquer, Dolores; Arós, Fernando; Gómez-Gracia, E.; Ruiz-Gutiérrez, Valentina; Fiol Sala, Miguel; Lapetra, José; Lamuela Raventós, Rosa Ma.; Serra Majem, Lluís; Pintó Sala, Xavier; Basora-Gallisá, Josep; Muñoz, Miguel Ángel; Sorlí, J. V.; Martínez, J. A.; Martínez-González, Miguel Ángel, 1957-
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