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Alanine aminotransferase: A target to improve utilisation of dietary nutrients in aquaculture
Metón Teijeiro, Isidoro; Salgado Martín, María del Carmen; Anemaet, Ida Guurtje; González, Juan D.; Fernández González, Felipe Javier; Vázquez Baanante, Ma. Isabel
Universitat de Barcelona
Alanine aminotransferase (ALT) is a sensitive marker of dietary protein utilisation in fish. Three ALT isoforms (cALT1, cALT2 and mALT) encoded by two genes have been isolated from gilthead sea bream (Sparus aurata). Molecular characterization of ALT isozymes and gene promoters suggest involvement of cALT1 and mALT in postprandial use of dietary amino acids, while cALT2 seems associated to hepatic gluconeogenesis. Inhibition of hepatic cytosolic ALT activity stimulates pyruvate kinase and decreases the renewal rate of alanine in S. aurata. These findings point to ALT as a target to spare protein and improve catabolism of dietary carbohydrates in cultured fish.
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/67430
Transferases
Suplements nutritius
Orada
Aqüicultura
Bioquímica
Biologia molecular
Transferases
Dietary supplements
Sparus aurata
Aquaculture
Biochemistry
Molecular biology
(c) Research Signpost, 2015
info:eu-repo/semantics/bookPart
Research Signpost
         

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