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Zebrafish as a model for developmental toxicity assessment
Teixidó Condomines, Elisabet; Piqué Benages, Maria Esther; Boix Sabria, Núria; Llobet Mallafré, Joan M. (Joan Maria); Gómez Catalán, Jesús
Universitat de Barcelona
The zebrafish embryo has emerged as promising alternative model for traditional in vivo developmental toxicological screening due to their advantageous characteristics as their small size and transparency. In this paper, we reviewed the applicability of the zebrafish embryo model in some relevant areas to human toxicology as developmental toxicity, cardiovascular toxicity and neurotoxicity (behavioral assessment). Despite the promising results, further optimization and testing of more substances as well as a harmonized methodology is needed to streamline the methods and make the assay conducive to medium-throughput.
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/67430
Peix zebra
Toxicologia
Zebra fish
Toxicology
(c) Research Signpost, 2015
info:eu-repo/semantics/bookPart
Research Signpost
         

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