This paper describes a new seismic protection system for timber platform frame buildings, either for new construction or retrofit. The system consists in connecting the timber frame to a steel structure that includes hysteretic energy dissipators designed to absorb most of the seismic input energy thus protecting the timber frame and the other steel members; alternatively, the system might use other types of dissipative devices. The steel structure consists of four steel stacks (located at each of the four façades) and steel collectors embracing each slab; the stacks and the collectors are connected, at each floor level, through the energy dissipators. The steel structure is self-supporting, that is, the timber frame is not affected by horizontal actions and can be designed without accounting for any seismic provision; in turn, the steel members do not participate in the main load-carrying system. The timber-steel interface is designed to avoid any stress concentration in the transfer of horizontal forces and to guarantee that the yielding of the dissipators occurs prior to any timber failure. The energy dissipation capacity of the suggested system is discussed, and an application example on a six-story timber building is presented; this case corresponds to highly demanding conditions because of the relatively large building height and weight, the high local seismicity, and the soft soil condition. This research belongs to a wider project aiming to promote the structural use of timber by improving the seismic capacity of wooden buildings; this research includes experiments and advanced numerical simulation. Copyright © 2014 John Wiley & Sons, Ltd.