Per accedir als documents amb el text complet, si us plau, seguiu el següent enllaç:

Selective detection of dopamine combining multilayers of conducting polymers with gold nanoparticles
Fabregat Jové, Georgina; Armelín Diggroc, Elaine Aparecida; Alemán Llansó, Carlos
Universitat Politècnica de Catalunya. Departament d'Enginyeria Química; Universitat Politècnica de Catalunya. IMEM - Innovació, Modelització i Enginyeria en (BIO) Materials
Electrodes based on the combination of three-layered films formed by two different conducting polymers and gold nanoparticles have been developed for the selective voltammetric determination of dopamine in mixtures with ascorbic acid and uric acid and human urine samples with real interferents. Voltammetric studies of solution mixtures indicate that electrodes formed by alternated layers of poly(3,4-ethylenedioxithiophene) (internal and external layer) and poly(N-methylpyrrole) (intermediate layer) show the best performance in terms of sensitivity and resolution. Furthermore, the sensitivity of such three-layered electrodes increases only slightly after coating its surface with gold nanoparticles (AuNPs), indicating that the catalytic effect typically played by AuNPs in the oxidation of dopamine is less effective in this case. Electrochemical pretreatments based on the application of consecutive oxidation-reduction cycles to electrodes before the detection process have been found to improve the selectivity without altering the sensitivity. On the other hand, the flux of dopamine to the three-layered surface increases linearly with the scan rate. The detection limit for these electrodes is around 10 µM DA in mixtures with uric acid, ascorbic acid, and cetaminophen, decreasing to 2-3 µM in the absence of such interferents. The utility of three-layered electrodes as sensors has also been demonstrated by determining DA in human samples with real interferents.
Peer Reviewed
Àrees temàtiques de la UPC::Enginyeria química
Conducting polymers
Engineering controlled terms: Amines
Ascorbic acid
Catalytic oxidation
Conducting polymers
Metal nanoparticles
Polímers -- Conductivitat tèrmica
Attribution-NonCommercial-NoDerivs 3.0 Spain

Mostra el registre complet del document

Documents relacionats

Altres documents del mateix autor/a

Fabregat Jové, Georgina; Cruz Teixeira Dias, Bruno José da; Valle Mendoza, Luis Javier del; Armelín Diggroc, Elaine Aparecida; Estrany Coda, Francesc; Alemán Llansó, Carlos
Hocevar, Marcele A.; Fabregat Jové, Georgina; Armelín Diggroc, Elaine Aparecida; Ferreira, Carlos Arthur; Alemán Llansó, Carlos
Alemán Llansó, Carlos; Pérez Madrigal, Maria del Mar; Fabregat Jové, Georgina; Armelín Diggroc, Elaine Aparecida
Fabregat Jové, Georgina; Casanovas Salas, Jordi; Redondo Negrete, Edurne; Armelín Diggroc, Elaine Aparecida; Alemán Llansó, Carlos
Fabregat Jové, Georgina; Osorio Madrigal, Joaquin; Castedo Rodríguez, Alejandra; Armelín Diggroc, Elaine Aparecida; Buendía Morales, Jorge Juan; Llorca Piqué, Jordi; Alemán Llansó, Carlos