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Cyclosporine A, an alternative to the oral lichen planus erosive treatment
López López, José, 1958-; Roselló Llabrés, Xavier
Universitat de Barcelona
We present a double-blind study in two groups afflicted with oral lichen planus erythematous of long evolution and resistant to other treatments. We tested on it a treatment with Cyclosporine A (CyA) which had been successfully used before by many dermatologists. In the group A we used mouthwashes with a 5 ml Cyclosporine A solution to a 10% in olive oil of 0.4 degrees of acidity for five minutes, three times a day for eight weeks. In the control group we used acetonide of triamcinolone 01% in aqueous solution. Patients in group A improved considerably in their symptomatology in a 90% against a 60% in group B. In group A we could appreciate a disappearance of the symptomatology after two weeks of treatment in 60% of patients against 30% in group B. CyA can be an alternative to the conventional treatments in the acute period of lichen planus although it can not be considered as a first option drug because of the high cost of the treatment. For long term, results are not so good and we consider that extensive studies are necessary
2014-07-14
Ciclosporina
Higiene bucal
Higiene dental
Desinfectants
Mucosa oral
Líquens
Cyclosporine
Oral hygiene
Dental hygiene
Disinfectants
Oral mucosa
Lichens
(c) Groupement International pour la Recherche Scientifique en Stomatologie et Odontologie, 1995
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info:eu-repo/semantics/publishedVersion
Groupement International pour la Recherche Scientifique en Stomatologie et Odontologie
         

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