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Cyclosporine A, an alternative to the oral lichen planus erosive treatment
López López, José, 1958-; Roselló Llabrés, Xavier
Universitat de Barcelona
We present a double-blind study in two groups afflicted with oral lichen planus erythematous of long evolution and resistant to other treatments. We tested on it a treatment with Cyclosporine A (CyA) which had been successfully used before by many dermatologists. In the group A we used mouthwashes with a 5 ml Cyclosporine A solution to a 10% in olive oil of 0.4 degrees of acidity for five minutes, three times a day for eight weeks. In the control group we used acetonide of triamcinolone 01% in aqueous solution. Patients in group A improved considerably in their symptomatology in a 90% against a 60% in group B. In group A we could appreciate a disappearance of the symptomatology after two weeks of treatment in 60% of patients against 30% in group B. CyA can be an alternative to the conventional treatments in the acute period of lichen planus although it can not be considered as a first option drug because of the high cost of the treatment. For long term, results are not so good and we consider that extensive studies are necessary
Higiene bucal
Higiene dental
Mucosa oral
Oral hygiene
Dental hygiene
Oral mucosa
(c) Groupement International pour la Recherche Scientifique en Stomatologie et Odontologie, 1995
Groupement International pour la Recherche Scientifique en Stomatologie et Odontologie

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