Título:
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First enantioselective synthesis of isagarin, a natural product isolated from Pentas longiflora Oliv.
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Autor/a:
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Jacobs, Jan; Claessens, Sven; Mol, Eva de; El Hady, Samir; Minguillón Llombart, Cristina; Álvarez Domingo, Mercedes; Kimpe, Norbert de
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Otros autores:
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Universitat de Barcelona |
Abstract:
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For the first time, an enantioselective synthesis of both 1R,4S-isagarin 1a and 1S,4R-isagarin 1b was achieved starting from 1,4-dimethoxy-2-vinylnaphtalene 2. The key steps involve a Sharpless asymmetric dihydroxylation and reaction with an acetonylating pyridinium ylid. |
Materia(s):
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-Síntesi asimètrica -Productes naturals -Asymmetric synthesis -Natural products |
Derechos:
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(c) Elsevier B.V., 2010
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Tipo de documento:
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Artículo Artículo - Versión aceptada |
Editor:
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Elsevier B.V.
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Compartir:
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