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Computational modeling of electromechanical propagation in the helical ventricular anatomy of the heart
Marcé Nogué, Jordi; Fortuny Anguera, Gerard; Ballester Rodés, Manel; Carreras Costa, Francesc; Roure Fernández, Francisco
Universitat Politècnica de Catalunya. Departament de Resistència dels Materials i Estructures en Enginyeria; Universitat Politècnica de Catalunya. LITEM - Laboratori per a la Innovació Tecnològica d'Estructures i Materials; Universitat Politècnica de Catalunya. REMM - Grup de Recerca en Estructures i Mecànica de Materials
The classical interpretation of myocardial activation assumes that the myocardium is homogeneous and that the electrical propagation is radial. However, anatomical studies have described a layered anatomical structure resulting from a continuous anatomical helical disposition of the myocardial fibers. To further investigate the sequence of electromechanical propagation based on the helical architecture of the heart, a simplified computational model was designed. This model was then used to test four activation patterns, which were generated by propagating the action potential along the myocardial band from different activation sites.
Peer Reviewed
Àrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica
Àrees temàtiques de la UPC::Ciències de la salut::Medicina
Computational biology
Myocardium
Fibers
Helical myocardial ventricular band
Electro-mechanical sequence
Activation
Action potential
Cardiac mechanics
Biologia computacional
info:eu-repo/semantics/submittedVersion
Article
Elsevier
         

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