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Salivary cotinine concentrations in daily smokers in Barcelona, Spain: a cross-sectional study
Fu Balboa, Marcela; Fernández Muñoz, Esteve; Martínez Sánchez, Jose M.; Pascual, José A.; Schiaffino, Anna; Agudo Trigueros, Antonio; Ariza, Carles; Borràs Andrés, Josep Maria; Samet, Jonathan M.
Universitat de Barcelona
Background: Characterizing and comparing the determinant of cotinine concentrations in different populations should facilitate a better understanding of smoking patterns and addiction. This study describes and characterizes determinants of salivary cotinine concentration in a sample of Spanish adult daily smoker men and women. Methods: A cross-sectional study was carried out between March 2004 and December 2005 in a representative sample of 1245 people from the general population of Barcelona, Spain. A standard questionnaire was used to gather information on active tobacco smoking and passive exposure, and a saliva specimen was obtained to determine salivary cotinine concentration. Two hundred and eleven adult smokers (>16 years old) with complete data were included in the analysis. Determinants of cotinine concentrations were assessed using linear regression models. Results: Salivary cotinine concentration was associated with the reported number of cigarettes smoked in the previous 24 hours (R2 = 0.339; p < 0.05). The inclusion of a quadratic component for number of cigarettes smoked in the regression analyses resulted in an improvement of the fit (R2 = 0.386; p < 0.05). Cotinine concentration differed significantly by sex, with men having higher levels. Conclusion: This study shows that salivary cotinine concentration is significantly associated with the number of cigarettes smoked and sex, but not with other smoking-related variables.
Nicotina
Saliva
Fumadors
Barcelona (Catalunya)
Mètodes estadístics
Nicotine
Saliva
Cigarette smokers
Barcelona (Catalonia)
Statistical methods
cc-by (c) Fu et al., 2009
http://creativecommons.org/licenses/by/3.0/es
Artículo
BioMed Central
         

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