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Use of Gene Ontology semantic information in protein interaction data visualization
Massanet Vila, Raimon; Caminal Magrans, Pere; Perera Lluna, Alexandre
Universitat Politècnica de Catalunya. Departament d'Enginyeria de Sistemes, Automàtica i Informàtica Industrial; Universitat Politècnica de Catalunya. SISBIO - Senyals i Sistemes Biomèdics
The Gene Ontology project is an effort to structure knowledge on biological products and processes by adding semantic information to them. This is done in a systematic way so that this additional information can be automatically processed. In this contribution a protein-protein interaction visualization algorithm is proposed, which combines protein interaction data with Gene Ontology semantic information. The information is integrated using a semantic distance measure defined in ontologies or taxonomies. Multidimensional scaling is applied to this measure and the output complements protein interaction data in building an interaction visualization map.
Peer Reviewed
Àrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica::Bioinformàtica
Biology computing
Data visualisation
Ontologies (artificial intelligence)
Information services
Proteomics
Gene ontology project
Ontologies (Recuperació de la informació)
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
IEEE Press. Institute of Electrical and Electronics Engineers
         

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