Título:
|
Vitamin D deficiency is associated with the presence and severity of diabetic retinopathy in type 2 Diabetes Mellitus
|
Autor/a:
|
Alcubierre Calvo, Núria; Valls Marsal, Joan; Rubinat, Esther; Cao, Gonzalo; Esquerda, Aureli; Traveset, Alicia; Granado Casas, Minerva; Jurjo Campo, Carmen; Mauricio Puente, Dídac
|
Abstract:
|
There is very few evidences on the role of vitamin D in the development of diabetic retinopathy. The aim of the current study was to explore whether there is an association of vitamin D status and diabetic retinopathy in type 2 diabetes. Two groups of patients were selected: 139 and 144 patients with and without retinopathy, respectively, as assessed by an experienced ophthalmologist. Subjects with advanced late diabetic complications were excluded to avoid confounding biases. 25-Hydroxy-vitamin D3 (25(OH)D) concentrations and vitamin D deficiency were associated with the presence of diabetic retinopathy. Additionally, patients with more advanced stages of retinopathy (grades 2 4) had lower concentrations of 25(OH)D and were more frequently vitamin D deficient as compared with patients not carrying this eye complication. In conclusion, our study confirms the association of vitamin D deficiency with the presence and severity of diabetic retinopathy in type 2 diabetes. Further experimental and prospective studies on this issue are clearly warranted. |
Fecha de creación:
|
00-05-2015 |
Materia(s):
|
Complicacions de la diabetis Malalties de la retina Vitamina D Diabetes complications Retinal diseases Vitamin D |
Derechos:
|
http://creativecommons.org/licenses/by/3.0/es
cc-by (c) Alcubierre Calvo, Núria et al., 2015 |
Tipo de documento:
|
Artículo |
Editor:
|
Hindawi Publishing Corporation
|
Compartir:
|
|