| dc.contributor.author |
Torner Gràcia, Núria |
| dc.contributor.author |
Broner, Sonia |
| dc.contributor.author |
Martinez, Ana |
| dc.contributor.author |
Tortajada, Cecilia |
| dc.contributor.author |
Garcia de Olalla, Patricia |
| dc.contributor.author |
Barrabeig i Fabregat, Irene |
| dc.contributor.author |
Sala, Maria Rosa |
| dc.contributor.author |
Camps, Neus |
| dc.contributor.author |
Minguell, Sofia |
| dc.contributor.author |
Álvarez, Josep |
| dc.contributor.author |
Ferrús, Gloria |
| dc.contributor.author |
Torra, Roser |
| dc.contributor.author |
Godoy i García, Pere |
| dc.contributor.author |
Domínguez García, Àngela |
| dc.date |
2015-05-19T11:11:00Z |
| dc.date |
2015-05-19T11:11:00Z |
| dc.date |
2012 |
| dc.identifier |
1932-6203 |
| dc.identifier |
http://hdl.handle.net/10459.1/48240 |
| dc.identifier |
https://doi.org/10.1371/journal.pone.0031339 |
| dc.identifier.uri |
http://hdl.handle.net/10459.1/48240 |
| dc.description |
Even though hepatitis A mass vaccination effectiveness is high, outbreaks continue to occur. The aim of this study was to
investigate the association between duration and characteristics of hepatitis A outbreaks. Hepatitis A (HA) outbreaks
reported between 1991 and 2007 were studied. An outbreak was defined as $2 epidemiologically-linked cases with $1
case laboratory-confirmed by detection of HA immunoglobulin M (IgM) antibodies. Relationships between explanatory
variables and outbreak duration were assessed by logistic regression. During the study period, 268 outbreaks (rate 2.45 per
million persons-year) and 1396 cases (rate 1.28 per 105 persons-year) were reported. Factors associated with shorter
duration were time to intervention (OR = 0.96; 95% CI: 0.94–0.98) and school setting (OR = 0.39; 95% CI: 0.16–0.92). In
person-to-person transmission outbreaks only time to intervention was associated with shorter outbreak duration
(OR = 0.96; 95% CI: 0.95–0.98). The only variables associated with shorter outbreak duration were early administration of IG
or vaccine and a school setting. Timely reporting HA outbreaks was associated with outbreak duration. Making confirmed
HA infections statutory reportable for clinical laboratories could diminish outbreak duration. |
| dc.language |
eng |
| dc.publisher |
Public Library of Science |
| dc.relation |
Reproducció del document publicat a https://doi.org/10.1371/journal.pone.0031339 |
| dc.relation |
PLoS One, 2012, vol. 7, núm. 2, e31339 |
| dc.rights |
cc-by, (c) Torner et al., 2012 |
| dc.rights |
http://creativecommons.org/licenses/by/3.0/es/ |
| dc.rights |
info:eu-repo/semantics/openAccess |
| dc.title |
Factors associated to duration of hepatitis A outbreaks: implications for control |
| dc.type |
article |
| dc.type |
publishedVersion |
