Para acceder a los documentos con el texto completo, por favor, siga el siguiente enlace: http://hdl.handle.net/2445/111962

Título:	Genetic variants of innate immune receptors and infections after liver transplantation.
Autor/a:	Sanclemente, Gemma; Moreno Camacho, Ma. Asunción; Navasa, Miquel; Lozano Soto, Francisco; Cervera, Carlos
Otros autores:	Universitat de Barcelona
Abstract:	Infection is the leading cause of complication after liver transplantation, causing morbidity and mortality in the first months after surgery. Allograft rejection is mediated through adaptive immunological responses, and thus immunosuppressive therapy is necessary after transplantation. In this setting, the presence of genetic variants of innate immunity receptors may increase the risk of post-transplant infection, in comparison with patients carrying wild-type alleles. Numerous studies have investigated the role of genetic variants of innate immune receptors and the risk of complication after liver transplantation, but their results are discordant. Toll-like receptors and mannose-binding lectin are arguably the most important studied molecules; however, many other receptors could increase the risk of infection after transplantation. In this article, we review the published studies analyzing the impact of genetic variants in the innate immune system on the development of infectious complications after liver transplantation.
Materia(s):	-Trasplantament hepàtic -Morbiditat -Immunitat -Infeccions -Hepatic transplantation -Morbidity -Immunity -Infections
Derechos:	cc-by-nc (c) Sanclemente, Gemma et al., 2014 http://creativecommons.org/licenses/by-nc/3.0/es
Tipo de documento:	Artículo Artículo - Versión publicada
Editor:	Baishideng Publishing Group
Compartir:

Mostrar el registro completo del ítem