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Título:	Comment on ‘protein–protein binding affinity prediction from amino acid sequence
Autor/a:	Moal, Iain H.; Fernández-Recio, Juan
Otros autores:	Barcelona Supercomputing Center
Abstract:	Predicting the strength of interactions between globular proteins is a central and important topic in structural bioinformatics (Moal et al., 2013). The amino acid sequence represents the chemical bonding in a protein which, along with the solvent, dictates how it folds into an ensemble of thermally accessible states. In turn, structure specifies the strength and identity of its binding partners, by establishing the specific arrangements of intermolecular interactions and the intramolecular strain required to achieve them.
Abstract:	IHM received funding from the People Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement PIEF-GA-2012-327899.
Abstract:	Peer Reviewed
Materia(s):	-Àrees temàtiques de la UPC::Enginyeria biomèdica -Protein-protein interactions -Protein–protein interactions -Amino acid sequence -Proteïnes--Enginyeria genètica
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Tipo de documento:	Artículo - Versión publicada Artículo
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